Interventions to treat pain in paediatric CFS/ME: a systematic review

BackgroundPaediatric chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is common (prevalence 1%–2%). Two-thirds of children experience moderate or severe pain, which is associated with increased fatigue and poorer physical function. However, we do not know if treatment for CFS/ME improves...

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Bibliographic Details
Published in:BMJ paediatrics open 2020-03, Vol.4 (1), p.e000617
Main Authors: Ascough, Caitlin, King, Hayley, Serafimova, Teona, Beasant, Lucy, Jackson, Sophie, Baldock, Luke, Pickering, Anthony Edward, Brooks, Jonathan, Crawley, Esther
Format: Article
Language:English
Subjects:
Bias
Chronic fatigue syndrome
Encephalomyelitis
Intervention
Pain
Patients
Pediatrics
Systematic review
Teenagers
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Summary:BackgroundPaediatric chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is common (prevalence 1%–2%). Two-thirds of children experience moderate or severe pain, which is associated with increased fatigue and poorer physical function. However, we do not know if treatment for CFS/ME improves pain.ObjectiveIdentify whether specialist treatment of paediatric CFS/ME improves pain.MethodsWe conducted a detailed search in MEDLINE, EMBASE, PsycINFO and the Cochrane Library. Two researchers independently screened texts published between 1994 and 24 January 2019 with no language restrictions. Inclusion criteria were (1) randomised controlled trials and observational studies; (2) participants aged
ISSN:2399-9772
2399-9772
DOI:10.1136/bmjpo-2019-000617