Endobronchial Ultrasound-guided Transbronchial Needle Aspiration 
in the Diagnosis of Intrathoracic Metastasis from Extrapulmonary Malignancy

Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) has been widely applied in diagnosing mediastinal and hilar adenopathy. This study is further to evaluate value and safety of EBUS-TBNA in diagnosing intrathoracic metastasis from extrapulmonary malignancy. Prospectively an...

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Bibliographic Details
Published in:Zhongguo fei ai za zhi 2015-05, Vol.18 (5), p.295-300
Main Authors: Sun, Jiayuan, Bao, Liang, Teng, Jiajun, Zhong, Runbo, Weng, Weiqiong, Zhang, Qin, Han, Baohui
Format: Article
Language:Chinese
Subjects:
Adult
Aged
Biopsy
Biopsy, Fine-Needle - methods
Breast cancer
Endobronchial ultrasound
Endosonography - methods
Extrapulmonary neoplasm
Female
Humans
Immunohistochemistry
Lung cancer
Lung Neoplasms - pathology
Lymphatic system
Male
Mediastinal Neoplasms - diagnosis
Mediastinal Neoplasms - diagnostic imaging
Mediastinal Neoplasms - pathology
Mediastinal Neoplasms - secondary
Mediastinum - diagnostic imaging
Mediastinum - pathology
Metastasis
Middle Aged
Mycobacterium
Needle aspiration
Neoplasm Metastasis
Ostomy
Systematic review
Tomography
Tuberculosis
Ultrasonic imaging
Young Adult
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Summary:Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) has been widely applied in diagnosing mediastinal and hilar adenopathy. This study is further to evaluate value and safety of EBUS-TBNA in diagnosing intrathoracic metastasis from extrapulmonary malignancy. Prospectively analysis of 41 patients suspected intrathoracic metastasis from previous diagnosed/concurrent extrapulmonary malignancies in Shanghai Chest Hospital, with radiologic findings showing mediastinal/hilar lymph node enlargement or intrapulmonary lesion requiring EBUS-TBNA examination for pathological diagnosis. 41 candidate patients enrolled, and 67 mediastinal/hilar lymph nodes and 5 intrapulmonary lesions were aspirated. 14 intrathoracic metastasis, 10 primary lung cancer, 9 reactive lymphadenitis, 4 sarcoid-like reactions, and 1 tuberculosis was diagnosed by EBUS-TBNA. Sensitivity and accuracy of EBUS-TBNA in diagnosing intrathoracic metastasis was 87.50% and 95.12%, respectively. Immunohistochemistry (IHC) was perfor
ISSN:1009-3419
1999-6187
DOI:10.3779/j.issn.1009-3419.2015.05.07