Antioxidants as a Potential Target against Inflammation and Oxidative Stress in Attention-Deficit/Hyperactivity Disorder

Psychostimulants and non-psychostimulants are the medications prescribed for the treatment of attention-deficit/hyperactivity disorder (ADHD). However, several adverse results have been linked with an increased risk of substance use and side effects. The pathophysiology of ADHD is not completely kno...

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Bibliographic Details
Published in:Antioxidants 2020-02, Vol.9 (2), p.176
Main Authors: Alvarez-Arellano, Lourdes, González-García, Nadia, Salazar-García, Marcela, Corona, Juan Carlos
Format: Article
Language:English
Subjects:
adhd
antioxidants
Antioxidants (Nutrients)
Attention deficit hyperactivity disorder
Health aspects
Inflammation
nrf2
Oxidative stress
Physiological aspects
Prevention
Review
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Summary:Psychostimulants and non-psychostimulants are the medications prescribed for the treatment of attention-deficit/hyperactivity disorder (ADHD). However, several adverse results have been linked with an increased risk of substance use and side effects. The pathophysiology of ADHD is not completely known, although it has been associated with an increase in inflammation and oxidative stress. This review presents an overview of findings following antioxidant treatment for ADHD and describes the potential amelioration of inflammation and oxidative stress using antioxidants that might have a future as multi-target adjuvant therapy in ADHD. The use of antioxidants against inflammation and oxidative conditions is an emerging field in the management of several neurodegenerative and neuropsychiatric disorders. Thus, antioxidants could be promising as an adjuvant ADHD therapy.
ISSN:2076-3921
2076-3921
DOI:10.3390/antiox9020176