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The impact of heavy alcohol consumption on cognitive impairment in young old and middle old persons

Dementia indicates a significant disease burden worldwide with increased population aging. This study aimed to investigate the impact of alcohol consumption on the risk of cognitive impairment in older adults. Participants ≥ 60 years were administered the Digit Symbol Substitution Test (DSST) to eva...

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Bibliographic Details
Published in:Journal of translational medicine 2022-04, Vol.20 (1), p.155-155, Article 155
Main Authors: Yen, Fu-Shun, Wang, Shiow-Ing, Lin, Shih-Yi, Chao, Yung-Hsiang, Wei, James Cheng-Chung
Format: Article
Language:English
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Summary:Dementia indicates a significant disease burden worldwide with increased population aging. This study aimed to investigate the impact of alcohol consumption on the risk of cognitive impairment in older adults. Participants ≥ 60 years were administered the Digit Symbol Substitution Test (DSST) to evaluate cognitive function in National Health and Nutrition Examination Survey (NHANES) cycles from 1999 to 2002 and 2011 to 2014 for enrollment in the present study. Participants were categorized into non-drinker, drinker, and heavy drinker groups. Logistic regression analyses were performed to explore associations between cognitive impairment and alcohol consumption. Multivariate analysis showed that older adults, men, people from minority races, persons with lower education or income levels, social difficulties, hypertension, or chronic kidney disease were significantly associated with a higher risk of cognitive impairment (all p 
ISSN:1479-5876
1479-5876
DOI:10.1186/s12967-022-03353-3