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A pilot study of scleral thickness in central serous chorioretinopathy using anterior segment optical coherence tomography
The aim of this study is to compare the scleral thickness of central serous chorioretinopathy (CSC) eyes with controls using anterior segment optical coherence tomography (AS OCT). This prospective case control study included 15 patients (15 eyes) with CSC and 15 age and gender matched healthy subje...
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Published in: | Scientific reports 2021-03, Vol.11 (1), p.5872-5872, Article 5872 |
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description | The aim of this study is to compare the scleral thickness of central serous chorioretinopathy (CSC) eyes with controls using anterior segment optical coherence tomography (AS OCT). This prospective case control study included 15 patients (15 eyes) with CSC and 15 age and gender matched healthy subjects. All subjects underwent spectral domain OCT with enhanced depth imaging and swept source AS OCT of temporal sclera. We investigated difference in scleral thickness between the two groups and relationship between choroidal and scleral thickness. Among the 15 eyes in the study group, 1 eye had acute CSC, 4 had recurrent CSC, 7 had inactive CSC, and 3 had chronic CSC. There was no significant difference in terms of age, gender, axial length and spherical equivalent between the two groups. The choroidal and scleral thickness of the study group were significantly greater than those of the control group (
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doi_str_mv | 10.1038/s41598-021-85229-y |
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P
< 0.001,
P
= 0.034). Choroidal thickness was positively correlated with scleral thickness (
P
= 0.031). A thick sclera along with a thick choroid were demonstrated in CSC eyes using AS OCT. Scleral characteristics might be involved in the pathogenesis of CSC by affecting outflow resistance of venous drainage in choroidal circulation.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-021-85229-y</identifier><identifier>PMID: 33712652</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/699/3161/3175 ; 692/699/3161/3176 ; 692/699/3161/3178 ; Gender ; Humanities and Social Sciences ; multidisciplinary ; Science ; Science (multidisciplinary) ; Tomography</subject><ispartof>Scientific reports, 2021-03, Vol.11 (1), p.5872-5872, Article 5872</ispartof><rights>The Author(s) 2021. corrected publication 2021</rights><rights>The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2021. corrected publication 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2021, corrected publication 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c634t-a43478c325295e1a434e680cd17d0aa519ff3bf2072c07d5bf04ef33ebeb75423</citedby><cites>FETCH-LOGICAL-c634t-a43478c325295e1a434e680cd17d0aa519ff3bf2072c07d5bf04ef33ebeb75423</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2548893743/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2548893743?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33712652$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Yun Ji</creatorcontrib><creatorcontrib>Lee, Yeon Jeong</creatorcontrib><creatorcontrib>Lee, Jae Yeon</creatorcontrib><creatorcontrib>Lee, Suhwan</creatorcontrib><title>A pilot study of scleral thickness in central serous chorioretinopathy using anterior segment optical coherence tomography</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>The aim of this study is to compare the scleral thickness of central serous chorioretinopathy (CSC) eyes with controls using anterior segment optical coherence tomography (AS OCT). This prospective case control study included 15 patients (15 eyes) with CSC and 15 age and gender matched healthy subjects. All subjects underwent spectral domain OCT with enhanced depth imaging and swept source AS OCT of temporal sclera. We investigated difference in scleral thickness between the two groups and relationship between choroidal and scleral thickness. Among the 15 eyes in the study group, 1 eye had acute CSC, 4 had recurrent CSC, 7 had inactive CSC, and 3 had chronic CSC. There was no significant difference in terms of age, gender, axial length and spherical equivalent between the two groups. The choroidal and scleral thickness of the study group were significantly greater than those of the control group (
P
< 0.001,
P
= 0.034). Choroidal thickness was positively correlated with scleral thickness (
P
= 0.031). A thick sclera along with a thick choroid were demonstrated in CSC eyes using AS OCT. 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Lee, Yeon Jeong ; Lee, Jae Yeon ; Lee, Suhwan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c634t-a43478c325295e1a434e680cd17d0aa519ff3bf2072c07d5bf04ef33ebeb75423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>692/699/3161/3175</topic><topic>692/699/3161/3176</topic><topic>692/699/3161/3178</topic><topic>Gender</topic><topic>Humanities and Social Sciences</topic><topic>multidisciplinary</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Yun Ji</creatorcontrib><creatorcontrib>Lee, Yeon Jeong</creatorcontrib><creatorcontrib>Lee, Jae Yeon</creatorcontrib><creatorcontrib>Lee, Suhwan</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Science Journals</collection><collection>Biological Science Database</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Yun Ji</au><au>Lee, Yeon Jeong</au><au>Lee, Jae Yeon</au><au>Lee, Suhwan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A pilot study of scleral thickness in central serous chorioretinopathy using anterior segment optical coherence tomography</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2021-03-12</date><risdate>2021</risdate><volume>11</volume><issue>1</issue><spage>5872</spage><epage>5872</epage><pages>5872-5872</pages><artnum>5872</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>The aim of this study is to compare the scleral thickness of central serous chorioretinopathy (CSC) eyes with controls using anterior segment optical coherence tomography (AS OCT). This prospective case control study included 15 patients (15 eyes) with CSC and 15 age and gender matched healthy subjects. All subjects underwent spectral domain OCT with enhanced depth imaging and swept source AS OCT of temporal sclera. We investigated difference in scleral thickness between the two groups and relationship between choroidal and scleral thickness. Among the 15 eyes in the study group, 1 eye had acute CSC, 4 had recurrent CSC, 7 had inactive CSC, and 3 had chronic CSC. There was no significant difference in terms of age, gender, axial length and spherical equivalent between the two groups. The choroidal and scleral thickness of the study group were significantly greater than those of the control group (
P
< 0.001,
P
= 0.034). Choroidal thickness was positively correlated with scleral thickness (
P
= 0.031). A thick sclera along with a thick choroid were demonstrated in CSC eyes using AS OCT. Scleral characteristics might be involved in the pathogenesis of CSC by affecting outflow resistance of venous drainage in choroidal circulation.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>33712652</pmid><doi>10.1038/s41598-021-85229-y</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | 692/699/3161/3175 692/699/3161/3176 692/699/3161/3178 Gender Humanities and Social Sciences multidisciplinary Science Science (multidisciplinary) Tomography |
title | A pilot study of scleral thickness in central serous chorioretinopathy using anterior segment optical coherence tomography |
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