Clinical efficacy and influencing factors of percutaneous kyphoplasty for osteoporotic vertebral compression fractures: a 10-year follow-up study

To date, few reports have evaluated the long-term outcome of percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCFs) and the factors influencing the long-term outcome of this procedure are uncertain. A total of 91 patients underwent PKP for thoracolumbar OVCFs from Ju...

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Bibliographic Details
Published in:BMC surgery 2024-01, Vol.24 (1), p.29-29, Article 29
Main Authors: Zhan, Zihao, Li, Ran, Fu, Dongming, Han, Hao, Wu, Yiang, Meng, Bin
Format: Article
Language:English
Subjects:
Age
Back pain
Back surgery
Bisphosphonates
Bone cements
Bone Cements - therapeutic use
Bone density
Bone implants
Bone mineral density
Bone surgery
Cement
Compression
Diabetes
Diabetes mellitus
Effectiveness
Female
Follow-Up Studies
Fractures
Fractures, Compression - surgery
Gender
Hospitalization
Humans
Hypertension
Injuries
Kyphoplasty
Kyphoplasty - methods
Male
Males
Orthopedic surgery
Osteoporosis
Osteoporotic fractures
Osteoporotic Fractures - surgery
Pain
Pain - complications
Pain - drug therapy
Patient outcome assessment
Patients
Polymethyl methacrylate
Quality of life
Regression analysis
Retrospective Studies
Risk factors
Segments
Spinal Fractures - etiology
Spinal Fractures - surgery
Statistical analysis
Statistical significance
Surgery
Trauma
Treatment Outcome
Vertebrae
Zoledronic acid
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Summary:To date, few reports have evaluated the long-term outcome of percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCFs) and the factors influencing the long-term outcome of this procedure are uncertain. A total of 91 patients underwent PKP for thoracolumbar OVCFs from June 2012 to December 2012. Pain Visual Analogue Scores (VAS) and Oswestry Disability Index (ODI) were recorded preoperatively and after 10-year follow-up. Factors that may affect surgical outcome, such as gender, age, height, weight, hypertension, diabetes, cause of injury, fracture segment, length of hospitalization, history of previous spinal surgery, preoperative bone mineral density (BMD), preoperative VAS and ODI scores, length of surgery, bone cement dosage, postoperative standardized anti-osteoporosis treatment, and other new vertebral fractures, were analyzed by multiple linear regression with VAS and ODI scores at the last follow-up. The correlation factors affecting the efficacy were analyzed. The preoperative and final follow-up pain VAS was 7.9 ± 1.1 and 2.2 ± 1.1. ODI scores were 30.4 ± 4.2 and 10.7 ± 2.6. The difference was statistically significant (P 
ISSN:1471-2482
1471-2482
DOI:10.1186/s12893-024-02322-5