Loading…
Prognostic significance of accelerated ventricular response during radiofrequency ablation of premature ventricular complexes
Accelerated ventricular response is frequently observed during radiofrequency ablation (RFA) of premature ventricular complexes (PVCs). We hypothesized that acceleration indicates an appropriate site and adequate injury to the arrhythmogenic tissue, and sought to investigate its value in predicting...
Saved in:
Published in: | Indian pacing and electrophysiology journal 2020-11, Vol.20 (6), p.231-236 |
---|---|
Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c4361-8bde7d105e6dceaf6a7fe273471c178dba2ee72a43ff3d5fae426993bbcaa3353 |
---|---|
cites | cdi_FETCH-LOGICAL-c4361-8bde7d105e6dceaf6a7fe273471c178dba2ee72a43ff3d5fae426993bbcaa3353 |
container_end_page | 236 |
container_issue | 6 |
container_start_page | 231 |
container_title | Indian pacing and electrophysiology journal |
container_volume | 20 |
creator | Patloori, Sirish Chandra Srinath Manickavasagam, Anand Chase, David Roshan, John |
description | Accelerated ventricular response is frequently observed during radiofrequency ablation (RFA) of premature ventricular complexes (PVCs). We hypothesized that acceleration indicates an appropriate site and adequate injury to the arrhythmogenic tissue, and sought to investigate its value in predicting the outcome.
We retrospectively analyzed RFA procedures performed for PVCs in our institution from 2011 to 2019.
Fifty-eight patients (29 male; age 42.7 ± 15.6 years) underwent 62 RFA procedures. The most common site was the right ventricular outflow tract (67.7%). Acute success was seen in 88.7%. Accelerated ventricular response was observed in 60.0% of the successful procedures. After a median follow-up of 14.0 months (IQR: 6.0–26.6 months), 16 patients had a recurrence. Recurrence was significantly lower in the group with acceleration than in the group without acceleration (12.5% vs. 57.1%; log-rank P |
doi_str_mv | 10.1016/j.ipej.2020.05.001 |
format | article |
fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_bb3275381a824468b4c22eb972b7d480</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0972629220300589</els_id><doaj_id>oai_doaj_org_article_bb3275381a824468b4c22eb972b7d480</doaj_id><sourcerecordid>2405302700</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4361-8bde7d105e6dceaf6a7fe273471c178dba2ee72a43ff3d5fae426993bbcaa3353</originalsourceid><addsrcrecordid>eNp9kk2L1TAUhosozof-ARfSpZtb89WmBRFkUGdgQBe6DifJaU3pTWrSXpyF_93UOw5zN64Skvc8OXnPWxSvKKkooc3bsXIzjhUjjFSkrgihT4pz0km2a1jHnj7anxUXKY2EsFp08nlxxplgbV2T8-L31xgGH9LiTJnc4F3vDHiDZehLMAYnjLCgLQ_ol-jMOkEsI6Y5-ISlXaPzQxnButBH_LmiN3cl6AkWF_yGmCPuYVkjngBM2M8T_sL0onjWw5Tw5f16WXz_9PHb1fXu9svnm6sPtzsjeEN3rbYoLSU1NtYg9A3IHpnkQlJDZWs1METJQPC-57buAQVruo5rbQA4r_llcXPk2gCjmqPbQ7xTAZz6exDioCBmCyZUWnMma95SaJkQTauFYQx1dlJLK1qSWe-PrHnVe8z95H_BdAI9vfHuhxrCQcmmy81ugDf3gBiyZWlRe5ey0xN4DGtSTJCaEybJJmVHqYkhpYj9wzOUqC0DalRbBtSWAUVqlTOQi14_bvCh5N_Qs-DdUYDZ8oPDqJJxeXRoXUSzZE_c__h_ALtAyA0</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2405302700</pqid></control><display><type>article</type><title>Prognostic significance of accelerated ventricular response during radiofrequency ablation of premature ventricular complexes</title><source>ScienceDirect Journals</source><source>PubMed</source><creator>Patloori, Sirish Chandra Srinath ; Manickavasagam, Anand ; Chase, David ; Roshan, John</creator><creatorcontrib>Patloori, Sirish Chandra Srinath ; Manickavasagam, Anand ; Chase, David ; Roshan, John</creatorcontrib><description>Accelerated ventricular response is frequently observed during radiofrequency ablation (RFA) of premature ventricular complexes (PVCs). We hypothesized that acceleration indicates an appropriate site and adequate injury to the arrhythmogenic tissue, and sought to investigate its value in predicting the outcome.
We retrospectively analyzed RFA procedures performed for PVCs in our institution from 2011 to 2019.
Fifty-eight patients (29 male; age 42.7 ± 15.6 years) underwent 62 RFA procedures. The most common site was the right ventricular outflow tract (67.7%). Acute success was seen in 88.7%. Accelerated ventricular response was observed in 60.0% of the successful procedures. After a median follow-up of 14.0 months (IQR: 6.0–26.6 months), 16 patients had a recurrence. Recurrence was significantly lower in the group with acceleration than in the group without acceleration (12.5% vs. 57.1%; log-rank P < 0.001). The 1-year recurrence rate was 6.5% in the acceleration group and 41.6% in the group without acceleration. On multivariable analysis the adjusted hazard ratio was 0.17 (95% CI, 0.04–0.64; Cox regression P = 0.009). The sensitivity, specificity, positive predictive, and negative predictive values of accelerated response to predict long-term success were 75.7%, 75.0%, 87.5%, and 57.2%, respectively.
The recurrence after PVC ablation is significantly lower when an accelerated response was observed at the successful location during RFA. This can be an additional useful marker of long-term success.</description><identifier>ISSN: 0972-6292</identifier><identifier>EISSN: 0972-6292</identifier><identifier>DOI: 10.1016/j.ipej.2020.05.001</identifier><identifier>PMID: 32428550</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Accelerated ventricular response ; Original ; Premature ventricular complexes ; Radiofrequency ablation ; Repetitive ventricular response</subject><ispartof>Indian pacing and electrophysiology journal, 2020-11, Vol.20 (6), p.231-236</ispartof><rights>2020 Indian Heart Rhythm Society</rights><rights>Copyright © 2020 Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. All rights reserved.</rights><rights>2020 Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. 2020 Indian Heart Rhythm Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4361-8bde7d105e6dceaf6a7fe273471c178dba2ee72a43ff3d5fae426993bbcaa3353</citedby><cites>FETCH-LOGICAL-c4361-8bde7d105e6dceaf6a7fe273471c178dba2ee72a43ff3d5fae426993bbcaa3353</cites><orcidid>0000-0002-7827-6774 ; 0000-0002-9435-8067</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691780/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0972629220300589$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,3536,27905,27906,45761,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32428550$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patloori, Sirish Chandra Srinath</creatorcontrib><creatorcontrib>Manickavasagam, Anand</creatorcontrib><creatorcontrib>Chase, David</creatorcontrib><creatorcontrib>Roshan, John</creatorcontrib><title>Prognostic significance of accelerated ventricular response during radiofrequency ablation of premature ventricular complexes</title><title>Indian pacing and electrophysiology journal</title><addtitle>Indian Pacing Electrophysiol J</addtitle><description>Accelerated ventricular response is frequently observed during radiofrequency ablation (RFA) of premature ventricular complexes (PVCs). We hypothesized that acceleration indicates an appropriate site and adequate injury to the arrhythmogenic tissue, and sought to investigate its value in predicting the outcome.
We retrospectively analyzed RFA procedures performed for PVCs in our institution from 2011 to 2019.
Fifty-eight patients (29 male; age 42.7 ± 15.6 years) underwent 62 RFA procedures. The most common site was the right ventricular outflow tract (67.7%). Acute success was seen in 88.7%. Accelerated ventricular response was observed in 60.0% of the successful procedures. After a median follow-up of 14.0 months (IQR: 6.0–26.6 months), 16 patients had a recurrence. Recurrence was significantly lower in the group with acceleration than in the group without acceleration (12.5% vs. 57.1%; log-rank P < 0.001). The 1-year recurrence rate was 6.5% in the acceleration group and 41.6% in the group without acceleration. On multivariable analysis the adjusted hazard ratio was 0.17 (95% CI, 0.04–0.64; Cox regression P = 0.009). The sensitivity, specificity, positive predictive, and negative predictive values of accelerated response to predict long-term success were 75.7%, 75.0%, 87.5%, and 57.2%, respectively.
The recurrence after PVC ablation is significantly lower when an accelerated response was observed at the successful location during RFA. This can be an additional useful marker of long-term success.</description><subject>Accelerated ventricular response</subject><subject>Original</subject><subject>Premature ventricular complexes</subject><subject>Radiofrequency ablation</subject><subject>Repetitive ventricular response</subject><issn>0972-6292</issn><issn>0972-6292</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNp9kk2L1TAUhosozof-ARfSpZtb89WmBRFkUGdgQBe6DifJaU3pTWrSXpyF_93UOw5zN64Skvc8OXnPWxSvKKkooc3bsXIzjhUjjFSkrgihT4pz0km2a1jHnj7anxUXKY2EsFp08nlxxplgbV2T8-L31xgGH9LiTJnc4F3vDHiDZehLMAYnjLCgLQ_ol-jMOkEsI6Y5-ISlXaPzQxnButBH_LmiN3cl6AkWF_yGmCPuYVkjngBM2M8T_sL0onjWw5Tw5f16WXz_9PHb1fXu9svnm6sPtzsjeEN3rbYoLSU1NtYg9A3IHpnkQlJDZWs1METJQPC-57buAQVruo5rbQA4r_llcXPk2gCjmqPbQ7xTAZz6exDioCBmCyZUWnMma95SaJkQTauFYQx1dlJLK1qSWe-PrHnVe8z95H_BdAI9vfHuhxrCQcmmy81ugDf3gBiyZWlRe5ey0xN4DGtSTJCaEybJJmVHqYkhpYj9wzOUqC0DalRbBtSWAUVqlTOQi14_bvCh5N_Qs-DdUYDZ8oPDqJJxeXRoXUSzZE_c__h_ALtAyA0</recordid><startdate>20201101</startdate><enddate>20201101</enddate><creator>Patloori, Sirish Chandra Srinath</creator><creator>Manickavasagam, Anand</creator><creator>Chase, David</creator><creator>Roshan, John</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-7827-6774</orcidid><orcidid>https://orcid.org/0000-0002-9435-8067</orcidid></search><sort><creationdate>20201101</creationdate><title>Prognostic significance of accelerated ventricular response during radiofrequency ablation of premature ventricular complexes</title><author>Patloori, Sirish Chandra Srinath ; Manickavasagam, Anand ; Chase, David ; Roshan, John</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4361-8bde7d105e6dceaf6a7fe273471c178dba2ee72a43ff3d5fae426993bbcaa3353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Accelerated ventricular response</topic><topic>Original</topic><topic>Premature ventricular complexes</topic><topic>Radiofrequency ablation</topic><topic>Repetitive ventricular response</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patloori, Sirish Chandra Srinath</creatorcontrib><creatorcontrib>Manickavasagam, Anand</creatorcontrib><creatorcontrib>Chase, David</creatorcontrib><creatorcontrib>Roshan, John</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Indian pacing and electrophysiology journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patloori, Sirish Chandra Srinath</au><au>Manickavasagam, Anand</au><au>Chase, David</au><au>Roshan, John</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic significance of accelerated ventricular response during radiofrequency ablation of premature ventricular complexes</atitle><jtitle>Indian pacing and electrophysiology journal</jtitle><addtitle>Indian Pacing Electrophysiol J</addtitle><date>2020-11-01</date><risdate>2020</risdate><volume>20</volume><issue>6</issue><spage>231</spage><epage>236</epage><pages>231-236</pages><issn>0972-6292</issn><eissn>0972-6292</eissn><abstract>Accelerated ventricular response is frequently observed during radiofrequency ablation (RFA) of premature ventricular complexes (PVCs). We hypothesized that acceleration indicates an appropriate site and adequate injury to the arrhythmogenic tissue, and sought to investigate its value in predicting the outcome.
We retrospectively analyzed RFA procedures performed for PVCs in our institution from 2011 to 2019.
Fifty-eight patients (29 male; age 42.7 ± 15.6 years) underwent 62 RFA procedures. The most common site was the right ventricular outflow tract (67.7%). Acute success was seen in 88.7%. Accelerated ventricular response was observed in 60.0% of the successful procedures. After a median follow-up of 14.0 months (IQR: 6.0–26.6 months), 16 patients had a recurrence. Recurrence was significantly lower in the group with acceleration than in the group without acceleration (12.5% vs. 57.1%; log-rank P < 0.001). The 1-year recurrence rate was 6.5% in the acceleration group and 41.6% in the group without acceleration. On multivariable analysis the adjusted hazard ratio was 0.17 (95% CI, 0.04–0.64; Cox regression P = 0.009). The sensitivity, specificity, positive predictive, and negative predictive values of accelerated response to predict long-term success were 75.7%, 75.0%, 87.5%, and 57.2%, respectively.
The recurrence after PVC ablation is significantly lower when an accelerated response was observed at the successful location during RFA. This can be an additional useful marker of long-term success.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>32428550</pmid><doi>10.1016/j.ipej.2020.05.001</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-7827-6774</orcidid><orcidid>https://orcid.org/0000-0002-9435-8067</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0972-6292 |
ispartof | Indian pacing and electrophysiology journal, 2020-11, Vol.20 (6), p.231-236 |
issn | 0972-6292 0972-6292 |
language | eng |
recordid | cdi_doaj_primary_oai_doaj_org_article_bb3275381a824468b4c22eb972b7d480 |
source | ScienceDirect Journals; PubMed |
subjects | Accelerated ventricular response Original Premature ventricular complexes Radiofrequency ablation Repetitive ventricular response |
title | Prognostic significance of accelerated ventricular response during radiofrequency ablation of premature ventricular complexes |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T07%3A35%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prognostic%20significance%20of%20accelerated%20ventricular%20response%20during%20radiofrequency%20ablation%20of%20premature%20ventricular%20complexes&rft.jtitle=Indian%20pacing%20and%20electrophysiology%20journal&rft.au=Patloori,%20Sirish%20Chandra%20Srinath&rft.date=2020-11-01&rft.volume=20&rft.issue=6&rft.spage=231&rft.epage=236&rft.pages=231-236&rft.issn=0972-6292&rft.eissn=0972-6292&rft_id=info:doi/10.1016/j.ipej.2020.05.001&rft_dat=%3Cproquest_doaj_%3E2405302700%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4361-8bde7d105e6dceaf6a7fe273471c178dba2ee72a43ff3d5fae426993bbcaa3353%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2405302700&rft_id=info:pmid/32428550&rfr_iscdi=true |