Natural-derived acetophenones: chemistry and pharmacological activities

Acetophenones are naturally occurring phenolic compounds which have found in over 24 plant families and also fungi strains. They are exist in both free or glycosides form in nature. The biological activities of these compounds have been assayed and reported including cytotoxicity, antimicrobial, ant...

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Bibliographic Details
Published in:Natural products and bioprospecting 2024-12, Vol.14 (1), p.28-28, Article 28
Main Authors: Ahmadpourmir, Hamid, Attar, Homayoun, Asili, Javad, Soheili, Vahid, Taghizadeh, Seyedeh Faezeh, Shakeri, Abolfazl
Format: Article
Language:English
Subjects:
Acetophenone
Acetophenones
Bioactivity
Biological activity
Biomedical and Life Sciences
Bioorganic Chemistry
Chemical activity
Chemistry
Cytotoxicity
Food Science
Fungi
Glycosides
Life Sciences
Medicinal Chemistry
Melicope
Natural products
Pesticides
Pharmacology/Toxicology
Phenolic compounds
Phenols
Phytochemicals
Plant Biochemistry
Plant Sciences
Review
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Summary:Acetophenones are naturally occurring phenolic compounds which have found in over 24 plant families and also fungi strains. They are exist in both free or glycosides form in nature. The biological activities of these compounds have been assayed and reported including cytotoxicity, antimicrobial, antimalarial, antioxidant and antityrosinase activities. Herein, we review the chemistry and biological activity of natural acetophenone derivatives that have been isolated and identified until January 2024. Taken together, it was reported 252 acetophenone derivatives in which the genera Melicope (69) and Acronychia (44) were the principal species as producers of acetophenones. Graphical Abstract
ISSN:2192-2195
2192-2209
DOI:10.1007/s13659-024-00447-x