Correlation of US-7 and US-9 Scores with Disease Activity Score using 28 Joint Counts (DAS28) in Patients with Rheumatoid Arthritis

• Published in: Iranian journal of medical sciences 2024-03, Vol.49 (3), p.167-175
• Main Authors: Ebadati, Sahar, Sahebari, Maryam, Ahmadzadeh, Amir Mahmoud, Emadzadeh, Maryam, Khoroushi, Farzaneh, Ragati Haghi, Hedieh, Giti, Ramesh, Aminzadeh, Behzad
• Format: Article
• Language: English
• Subjects: Adult; Arthritis; arthritis, rheumatoid; Arthritis, Rheumatoid - diagnostic imaging; Arthritis, Rheumatoid - pathology; Care and treatment; Diagnostic imaging; Humans; Iran; joints; Knee Joint - pathology; Middle Aged; Original; Rheumatoid arthritis; Rheumatoid factor; Synovitis - diagnostic imaging; Ultrasonic imaging; Ultrasonography; ultrasonography, doppler; Ultrasound imaging
• ISSN: 0253-0716; 1735-3688
• DOI: 10.30476/IJMS.2023.97776.2996

The attentive management of rheumatoid arthritis (RA) has attracted particular attention. The German 7-joint Ultrasound (US-7) is the first scoring system that combines bone erosions and soft tissue lesions in a single composite scoring system. This study aimed to assess the correlation between US-7 and Disease Activity Score Using 28 Joint Counts (DAS28) in clinically active RA patients. The efficacy of a novel ultrasound score-based system, the US-9 score (joints assessed with US-7 plus knees), was also compared with the standard US-7 score. All the RA patients referred to the outpatient rheumatology clinic of Ghaem Hospital, Mashhad, Iran, during 2019-2020 were included. 28 joints were clinically examined to calculate DAS28. Nine joints were assessed comprising the German US-7 plus knees using grayscale ultrasonography (GSUS) and power Doppler ultrasonography (PDUS). Retrieved data were analyzed by SPSS software, version 22. The Spearman Correlation test was used to find the correlation between DAS28 and ultrasonographic findings. The statistical significance level was set at P