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Anticoagulant rodenticide poisoning in calves - case report

ABSTRACT The aim was to report two cases of accidental Brodifacum poisoning in calves on a dairy farm. The animals presented a variable clinical picture of bleeding disorders with melena, epistaxis, orthopneic position, severe dyspnea, productive cough, coarse lung crackles, and expiratory groans. T...

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Published in:Arquivo brasileiro de medicina veterinária e zootecnia 2024, Vol.76 (6)
Main Authors: Almeida, R.A.T., Schunk, Y. S., Moraes, T. M. A., Moreira Júnior, C. A., Alves, S. R., Boeloni, J. N., Almeida, M. T. C., Rego, R.O.
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Language:English
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Summary:ABSTRACT The aim was to report two cases of accidental Brodifacum poisoning in calves on a dairy farm. The animals presented a variable clinical picture of bleeding disorders with melena, epistaxis, orthopneic position, severe dyspnea, productive cough, coarse lung crackles, and expiratory groans. The male died, the female was euthanized, and both were sent for necropsy. The anatomopathological findings revealed a predominantly bleeding diathesis in the animals. During the investigation, blood serum, liver and kidney samples were collected for toxicologic measurement, which revealed concentrations of coumarin derivatives < 0.100µg/kg in all samples. The combination of history, clinical-pathologic findings, and toxicologic results confirmed the diagnosis. RESUMO Objetivou-se relatar dois casos de intoxicação acidental por Brodifacum, em bezerros de uma fazenda de leite. Os animais apresentavam um quadro clínico variável de distúrbios hemorrágicos com melena, epistaxe, posição ortopneica, dispneia intensa, tosse produtiva, crepitação pulmonar grossa e gemidos expiratórios. O macho morreu, a fêmea foi submetida à eutanásia, e ambos foram encaminhados para exame necroscópico. Os achados anatomopatológicos revelaram, principalmente, um quadro de diátese hemorrágica nos animais. Durante o exame, foram coletadas amostras de soro sanguíneo, fígado e rins, para realização de dosagem toxicológica, obtendo-se como resultado concentrações de derivados de cumarina de
ISSN:0102-0935
1678-4162
1678-4162
DOI:10.1590/1678-4162-13234