Predictors of perioperative morbidity and mortality in adult living donor liver transplantations: report of results of a tertiary hospital

Background The aim of this study was to investigate the risk factors effective in perioperative morbidity and mortality in 161 living donor liver transplantations (LDLT). Results The most common indication for living donor transplantation was cryptogenic cirrhosis. The most common complication was b...

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Published in:Ain-Shams journal of anesthesiology 2020-11, Vol.12 (1), p.1-6, Article 60
Main Authors: Hizarci, Burcu, Karaaslan, Pelin, Ertugrul, Gokhan, Yilmaz, Mesut, Demiraran, Yavuz, Oz, Huseyin
Format: Article
Language:English
Subjects:
Critical Care Medicine
Intensive
Liver
Liver cirrhosis
Liver transplants
Living donor transplantation
Medicine
Medicine & Public Health
Morbidity
Mortality
Original Article
Sepsis
Surgery
Ventilation
Ventilators
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Summary:Background The aim of this study was to investigate the risk factors effective in perioperative morbidity and mortality in 161 living donor liver transplantations (LDLT). Results The most common indication for living donor transplantation was cryptogenic cirrhosis. The most common complication was biliary problems in 62.16% cases. Sepsis was the most common cause of in 52%. Patients in whom sepsis was observed, significantly prolonged stay under mechanical ventilation and prolonged ICU stay were detected. In patient group in whom mortality was observed, higher amounts of erythrocytes, fresh frozen plasma (FFP), and platelets were transfused, and patients remained longer under mechanical ventilation treatment, and in the ICU. Conclusion Perioperative morbidity and mortality was found to be significantly related with higher amounts of erythrocytes and FFP transfusions and longer operative and warm ischemia times. Sepsis was found to be the most common cause of mortality.
ISSN:2090-925X
1687-7934
2090-925X
DOI:10.1186/s42077-020-00094-7