Virologic suppression in patients with a documented M184V/I mutation based on the number of active agents in the antiretroviral regimen

Objectives: The optimal antiretroviral therapy for patients with the M184V/I mutation is not known. The primary objective of this study was to determine the efficacy of various antiretroviral therapies in patients with HIV and the M184V/I mutation based on the number of active antiretroviral agents....

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Bibliographic Details
Published in:SAGE open medicine 2020, Vol.8, p.2050312120960570-2050312120960570
Main Authors: Mouradjian, Mallory T, Heil, Emily L, Sueng, Hyunuk, Pandit, Neha Sheth
Format: Article
Language:English
Subjects:
Antiretroviral drugs
Confidence intervals
Drug therapy
Mutation
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Summary:Objectives: The optimal antiretroviral therapy for patients with the M184V/I mutation is not known. The primary objective of this study was to determine the efficacy of various antiretroviral therapies in patients with HIV and the M184V/I mutation based on the number of active antiretroviral agents. Methods: A retrospective chart review was conducted of 100 treatment-experienced patients harboring the M184V/I mutation seen at an urban HIV clinic. Efficacy was classified as percentage of patients with viral suppression defined as HIV RNA viral load
ISSN:2050-3121
2050-3121
DOI:10.1177/2050312120960570