Clinical and Financial Benefits of Intra-Articular Tranexamic Acid in Total Knee Arthroplasty

Purpose. To determine whether intra-articular tranexamic acid (TXA) use after total knee arthroplasty (TKA) results in decreased postoperative blood transfusion and length of hospital stay. Methods. Medical records of 1981 patients (mean age, 69.2 years) who underwent primary TKA with (n=1006) or wi...

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Bibliographic Details
Published in:Journal of orthopaedic surgery (Hong Kong) 2016-04, Vol.24 (1), p.3-6
Main Authors: Goyal, Navendu, Chen, Darren B, Harris, Ian A, Rowden, Neville, Kirsh, George, MacDessi, Samuel J
Format: Article
Language:English
Subjects:
Aged
Antifibrinolytic agents
Antifibrinolytic Agents - administration & dosage
Arthroplasty, Replacement, Knee
Blood Transfusion
Blood transfusions
Cost control
Cost Savings
Female
Hospitals
Humans
Injections, Intra-Articular
Joint Diseases - surgery
Joint replacement surgery
Joint surgery
Knee
Length of Stay
Male
Middle Aged
Molecular weight
Patients
Postoperative Care
Retrospective Studies
Thrombosis
Tranexamic Acid - administration & dosage
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Summary:Purpose. To determine whether intra-articular tranexamic acid (TXA) use after total knee arthroplasty (TKA) results in decreased postoperative blood transfusion and length of hospital stay. Methods. Medical records of 1981 patients (mean age, 69.2 years) who underwent primary TKA with (n=1006) or without (n=975) TXA use by any of 4 knee arthroplasty surgeons were reviewed. TXA (3000 mg/30ml) was administered via an epidural catheter into the knee joint after wound closure. Postoperative blood transfusion was given to patients with haemoglobin (Hb) level
ISSN:2309-4990
1022-5536
2309-4990
DOI:10.1177/230949901602400103