The change in Geriatric Nutritional Risk Index is associated with mortality in patients who start hemodialysis: Korean Renal Data Registry, 2016–2018

Malnutrition is common in patients undergoing hemodialysis (HD) and is associated with mortality. This study aimed to investigate the association between changes in nutrition status measured by the Geriatric Nutritional Risk Index (GNRI) and all-cause mortality in patients who started HD. A nationwi...

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Bibliographic Details
Published in:Scientific reports 2022-11, Vol.12 (1), p.20352-20352, Article 20352
Main Authors: Cho, AJin, Park, Se Yeon, Cha, Yo Seop, Park, Hayne Cho, Kim, Do Hyoung, Lee, Young-Ki
Format: Article
Language:English
Subjects:
692/4022
692/699
692/700
Aged
Geriatrics
Hemodialysis
Humanities and Social Sciences
Humans
Kidney Failure, Chronic - complications
Malnutrition
Mortality
multidisciplinary
Nutrition Assessment
Registries
Renal Dialysis - adverse effects
Republic of Korea - epidemiology
Retrospective Studies
Science
Science (multidisciplinary)
Trends
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Summary:Malnutrition is common in patients undergoing hemodialysis (HD) and is associated with mortality. This study aimed to investigate the association between changes in nutrition status measured by the Geriatric Nutritional Risk Index (GNRI) and all-cause mortality in patients who started HD. A nationwide retrospective cohort study was conducted based on the Korean Renal Data System database. Patients who started HD from January 2016 to December 2018, and were eligible for GNRI and GNRI trend were included. GNRI trend was a longitudinal change of GNRI, assessed by random slope in a mixed-effect model. Positive and negative random slopes in each patient were assigned to positive and negative GNRI trends. A total of 2313 patients were included and median follow-up period was 3.1 (2.6–3.7) years. GNRI values decreased over time (estimate − 1.212, 95% confidence interval (CI) − 1.116–0.692) and positive GNRI trend was associated with survival benefit (hazard ratio 0.55, 95% CI 0.36–0.84) after multivariate adjustment. These findings show that serial GNRI assessment, besides GNRI, is a useful prognostic factor for mortality in patients who start HD.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-24981-1