The first case of meningitis associated with SARS-CoV-2 BA.2 variant infection with persistent viremia

•Neurological disorders during COVID-19 are rare.•Plasmatic viremia could be persistent in patients who are immunocompromised.•Immunosuppression and blood-brain barrier injury could facilitate SARS-CoV-2 entry.•Central nervous system SARS-CoV-2 detection should be performed in neurological patients....

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Bibliographic Details
Published in:International journal of infectious diseases 2022-11, Vol.124, p.38-40
Main Authors: D'Abramo, Alessandra, Vita, Serena, Colavita, Francesca, Cimini, Eleonora, Haggiag, Shalom, Maffongelli, Gaetano, Valli, Maria Beatrice, Bevilacqua, Nazario, Corpolongo, Angela, Giancola, Maria Letizia, Maggi, Fabrizio, Agrati, Chiara, Nicastri, Emanuele
Format: Article
Language:English
Subjects:
Blood barrier damage
Case Report
COVID-19
Meningitis
Omicron
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Summary:•Neurological disorders during COVID-19 are rare.•Plasmatic viremia could be persistent in patients who are immunocompromised.•Immunosuppression and blood-brain barrier injury could facilitate SARS-CoV-2 entry.•Central nervous system SARS-CoV-2 detection should be performed in neurological patients. Severe neurological disorders and vascular events during COVID-19 have been described. Here, we describe the first case of a female patient infected with the SARS-CoV-2 BA.2 Omicron variant of concern with meningitis with newly diagnosed central demyelinating disease.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2022.09.011