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Metabolic syndrome: Nutri-epigenetic cause or consequence?

Metabolic syndrome is a cluster of conditions that results from the interplay of genetic and environmental factors, which increase the comorbidity risk of obesity, hyperglycemia, dyslipidemia, arterial hypertension, stroke, and cardiovascular disease. In this article, we review various high-impact s...

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Bibliographic Details
Published in:Heliyon 2023-11, Vol.9 (11), p.e21106-e21106, Article e21106
Main Authors: Silva-Ochoa, Alfonso D., Velasteguí, Erick, Falconí, Isaac B., García-Solorzano, Valeria I., Rendón-Riofrio, Angie, Sanguña-Soliz, Gabriela A., Vanden Berghe, Wim, Orellana-Manzano, Andrea
Format: Article
Language:English
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Summary:Metabolic syndrome is a cluster of conditions that results from the interplay of genetic and environmental factors, which increase the comorbidity risk of obesity, hyperglycemia, dyslipidemia, arterial hypertension, stroke, and cardiovascular disease. In this article, we review various high-impact studies which link epigenetics with metabolic syndrome by comparing each study population, methylation effects, and strengths and weaknesses of each research. We also discuss world statistical data on metabolic syndrome incidence in developing countries where the metabolic syndrome is common condition that has significant public health implications. [Display omitted]
ISSN:2405-8440
2405-8440
DOI:10.1016/j.heliyon.2023.e21106