C-reactive protein, D-dimer, erythrocyte sedimentation rate, and troponin in intensive care unit patients with COVID-19 in Iran

• Published in: Journal of research in medical sciences 2023-01, Vol.28 (1), p.56-56
• Main Authors: Salehi, Hassan, Pakzad, Bahram, Salehi, Marzieh, Abbasi, Saeed, Salehi, Mohammad, Naeini, Maryam
• Format: Article
• Language: English
• Subjects: C-reactive protein; coronavirus disease 2019; Coronaviruses; COVID-19; Erythrocyte sedimentation rate; Hospital patients; Intensive care; intensive care unit admission; prognostic factors; Short Communication
• ISSN: 1735-1995; 1735-1995; 1735-7136
• DOI: 10.4103/jrms.jrms_352_22

Background: The coronavirus disease 2019 (COVID-19) pandemic in Iran has led to a lack of intensive care unit (ICU) facilities. This study examines C-reactive protein (CRP), D-dimer, erythrocyte sedimentation rate (ESR), and troponin in ICU patients with COVID-19 in comparison to COVID-19 patients admitted to the wards in Iran. Materials and Methods: In a case-control study, troponin, CRP, ESR, and D-dimer were compared in the case samples of 109 COVID-19 patients admitted to the ICU, and in the control group, 140 COVID-19 patients admitted to the wards. Results: The mean of CRP (P < 0.001) and D-dimer (P < 0.001) was higher, whereas troponin (P < 0.001) was lower in patients admitted to the ICU, but no significant difference was observed between the values of ESR (P = 0.292) in the two groups. Conclusion: This study showed that the values of CRP and D-dimer were higher in patients admitted to the ICU, but no significant difference was observed between the values of ESR in the two groups.