Anticancer and Antimicrobial Properties of Inorganic Compounds/Nanomaterials

In the study of N. N. Farshori et al., silver nanoparticles (ND-AgNPs) were synthesized using an aqueous extract of Nepeta deflersiana plant, and their morpho-structural features were revealed by ultraviolet-visible spectroscopy, Fourier transforms infrared spectroscopy, X-ray diffraction, transmiss...

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Bibliographic Details
Published in:Bioinorganic chemistry and applications 2019-01, Vol.2019, p.6019632-2
Main Authors: Khan, Rais Ahmad, Tăbăcaru, Aurel, Ali, Farman, Koo, Bon H.
Format: Article
Language:English
Subjects:
Anticancer properties
Antimicrobial agents
Apoptosis
Cancer
Cancer therapies
Cell cycle
Cervical cancer
Chemotherapy
Cytotoxicity
E coli
Energy transmission
Feature extraction
Fourier transforms
Inorganic compounds
Investigations
Nanomaterials
Nanoparticles
Necrosis
Physiology
Proteins
Scanning electron microscopy
Silver
Transmission electron microscopy
X-ray diffraction
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Summary:In the study of N. N. Farshori et al., silver nanoparticles (ND-AgNPs) were synthesized using an aqueous extract of Nepeta deflersiana plant, and their morpho-structural features were revealed by ultraviolet-visible spectroscopy, Fourier transforms infrared spectroscopy, X-ray diffraction, transmission electron microscopy, scanning electron microscopy, and energy dispersive spectroscopy. The influence of cytotoxic concentrations of ND-AgNPs on oxidative stress markers, reactive oxygen species (ROS) generation, mitochondrial membrane potential (MMP), cell cycle arrest, and apoptosis/necrosis was also studied. According to the experimental spectroscopic data, DBDF2,6T could interact with the hPPARγ protein and formed a nonradiative ground-state complex of hPPARγ-DBDF2,6T, mainly through hydrophobic force.
ISSN:1565-3633
1687-479X
DOI:10.1155/2019/6019632