Serological Investigation of Occupational Exposure to Zoonotic Crimean-Congo Hemorrhagic Fever Infection

Crimean-Congo hemorrhagic fever (CCHF) is an acute and highly fatal disease. In this study, our aim was to compare and evaluate the prevalence of CCHF virus (CCHFV) antibody among occupational high-risk groups by using the enzyme-linked immunosorbent assay and draw attention to the occupational grou...

Full description

Saved in:
Bibliographic Details
Published in:The Eurasian journal of medicine 2020-06, Vol.52 (2), p.132-135
Main Authors: Aydin, Hakan, Uyanik, Muhammet Hamidullah, Karamese, Murat, Sozdutmaz, Ibrahim, Timurkan, Mehmet Ozkan, Gulen, Abdulkadir, Ozmen, Erkan, Aktas, Osman
Format: Article
Language:English
Subjects:
Blood donation
Employee attitudes
Enzyme-linked immunosorbent assay
Enzymes
Health aspects
Hemorrhagic fevers
Immunoglobulin G
Infection
Livestock
Medical research
Original
Prevalence studies (Epidemiology)
Zoonoses
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Crimean-Congo hemorrhagic fever (CCHF) is an acute and highly fatal disease. In this study, our aim was to compare and evaluate the prevalence of CCHF virus (CCHFV) antibody among occupational high-risk groups by using the enzyme-linked immunosorbent assay and draw attention to the occupational groups that are at high risk for CCHF infection in an endemic region for this zoonotic infection in Erzurum, Turkey. The antibody levels against CCHFV were surveyed among slaughterhouse workers, animal breeders, and veterinarians. The study population was composed of 72 participants having direct contact with animals and 19 blood donors who were not in direct contact with animals. The overall rate of CCHF immunoglobulin G positivity in risk groups was found to be 6.94% (5/72). CCHFV antibodies were found in 4 (12.5%) individuals of the animal breeder group. This ratio was considered significantly higher compared with the healthy control group. CCHFV antibodies were found in only one person (4.0%) who was an abattoir worker. In the veterinarian group, all people were found negative. In our study, the variables showing important associations with the prevalence of anti-CCHFV antibodies were livestock breeding, rural areas, and age. It was concluded that our region is endemic with regard to CCHF infection and persons who had direct contact with animals are at high risk. Thus, these participants must take necessary measures to protect themselves from CCHF and should be trained by health authorities.
ISSN:1308-8734
1308-8742
DOI:10.5152/eurasianjmed.2020.19176