Two cases of steroid dementia showing partial recovery during 2‐year follow‐up

Background Steroid dementia has been reported since the 1970s. In the current super‐aged society, it increasingly receives attention because of the growing number of elderly people that are medicated with steroids for systemic rheumatic disease. Case Presentation We report two cases of steroid demen...

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Bibliographic Details
Published in:PCN reports 2022-12, Vol.1 (4), p.e49-n/a
Main Authors: Ikeda, Natsuko, Yamada, Shinichi, Yamamoto, Masahiro, Tanaka, Katsunori, Fujii, Takao, Tsuji, Tomikimi, Kimoto, Sohei, Takahashi, Shun
Format: Article
Language:English
Subjects:
Alzheimer's disease
Angina pectoris
Atrophy
Case Report
Case Reports
cognition
Cognitive ability
Delirium
Dementia
elderly
Electroencephalography
Hospitals
Magnetic resonance imaging
Memory
Nuclear medicine
Older people
Patients
Pneumonia
recovery
Scintigraphy
steroid
Steroids
Thyroid gland
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Summary:Background Steroid dementia has been reported since the 1970s. In the current super‐aged society, it increasingly receives attention because of the growing number of elderly people that are medicated with steroids for systemic rheumatic disease. Case Presentation We report two cases of steroid dementia that were diagnosed as a result of careful observation of clinical symptoms and biological examination, including nuclear medicine tests. Cognitive and daily living functions were partially recovered in both cases after decrease or discontinuance of steroid medication in 2‐year follow‐up, but their daily living function could not be totally restored to premorbid level. Conclusion Cognitive dysfunction caused by steroids is suggested by these cases, although definitive diagnosis in these cases is not possible. It was partially reversible over the course of a few years, but some functional loss remains. Cognitive function should be assessed appropriately before, during, and after steroid treatment. Detailed differential diagnosis of neurodegenerative disorders and longitudinal follow‐up is required when cognitive dysfunction is observed after initiation of steroid therapy.
ISSN:2769-2558
2769-2558
DOI:10.1002/pcn5.49