Clinical and antimicrobial efficacy of NitrAdineTM-based disinfecting cleaning tablets in complete denture wearers

• Published in: Journal of applied oral science 2010-12, Vol.18 (6), p.560-565
• Main Authors: Silva-Lovato, Cláudia Helena, Wever, Bart de, Adriaens, Els, Paranhos, Helena de Freitas Oliveira, Watanabe, Evandro, Pisani, Maria Xavier, Souza, Rafael Freitas de, Ito, Isabel Yoko
• Format: Article
• Language: English
• Subjects: Biofilms; Complete denture; DENTISTRY, ORAL SURGERY & MEDICINE; Denture cleansers; Hygiene; Original
• ISSN: 1678-7757; 1678-7765; 1678-7757; 1678-7765
• DOI: 10.1590/S1678-77572010000600005

OBJECTIVE: This study evaluated the efficacy of NitrAdineTM-based disinfecting cleaning tablets for complete denture, in terms of denture biofilm removal and antimicrobial action. MATERIAL AND METHODS: Forty complete denture wearers (14 men and 26 women) with a mean age of 62.3±9.0 years were randomly assigned to two groups and were instructed to clean their dentures according to two methods: brushing (control) - 3 times a day with denture brush and tap water following meals; brushing and immersion (Experimental) - brushing the denture 3 times a day with denture brush and tap water following meals and immersion of the denture in NitrAdineTM-based denture tablets (Medical InterporousTM). Each method was used for 21 days. Denture biofilm was disclosed by a 1% neutral red solution and quantified by means of digital photos taken from the internal surface before and after the use of the product. Microbiological assessment was conducted to quantify Candida sp. RESULTS: An independent t-test revealed a significant lower biofilm percentage for the experimental group (4.7, 95% CI 2.4 to 7.9) in comparison with the control group (mean 37.5, 95% CI 28.2 to 48.1) (t38=7.996, p