Systemic ALK‐positive anaplastic large cell lymphoma with bilateral optic neurolymphomatosis resulting in permanent blindness

ALK‐positive ALCL can lead to rapid irreversible destruction of the optic pathway. Early treatment should be instituted in patients with CNS involvement or those at increased CNS risk. ALK‐positive ALCL can lead to rapid irreversible destruction of the optic pathway. Early treatment should be instit...

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Bibliographic Details
Published in:Clinical case reports 2020-12, Vol.8 (12), p.2629-2633
Main Authors: Seegobin, Karan, Alhaj Moustafa, Muhamad, Fischer, Deborah, Keller, Katelyn, Hastings, Jacquelyn, Kharfan‐Dabaja, Mohamed A., Ayala, Ernesto, Gupta, Vivek, Tun, Han W., Jiang, Liuyan
Format: Article
Language:English
Subjects:
ALK+ anaplastic large cell lymphoma
Biopsy
Bone marrow
Case Report
Case Reports
Cellular biology
Chemotherapy
Conflicts of interest
Dehydrogenases
Disease prevention
Lymphatic system
Lymphoma
Nervous system
neurolymphomatosis
Optic nerve
optic nerves
Patients
Remission (Medicine)
Transplants & implants
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Summary:ALK‐positive ALCL can lead to rapid irreversible destruction of the optic pathway. Early treatment should be instituted in patients with CNS involvement or those at increased CNS risk. ALK‐positive ALCL can lead to rapid irreversible destruction of the optic pathway. Early treatment should be instituted in patients with CNS involvement or those at increased CNS risk.
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.3231