Unusual Presentation of Acrodermatitis Chronica Atrophicans Resulting in Delay of Diagnosis and Inappropriate Treatment in Three Cases

Acrodermatitis chronica atrophicans (ACA) is not an infrequent condition in Europe. However, the characteristic skin lesions are often confused by non-dermatologists with other conditions. We report three unusual cases in which we made a definitive diagnosis of ACA complicated by cutaneous marginal...

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Bibliographic Details
Published in:Dermato 2024-05, Vol.4 (2), p.37-45
Main Authors: Gambichler, Thilo, Jridi, Rim, Bernd, Heinz-Wolfram, von Stemm, Andrea, Boms, Stefanie
Format: Article
Language:English
Subjects:
acrodermatitis chronica atrophicans
Borrelia burgdorferi
Lyme disease
lymphoma
polyneuropathy
pseudolymphoma
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Summary:Acrodermatitis chronica atrophicans (ACA) is not an infrequent condition in Europe. However, the characteristic skin lesions are often confused by non-dermatologists with other conditions. We report three unusual cases in which we made a definitive diagnosis of ACA complicated by cutaneous marginal zone lymphoma, juxta-articular fibrotic nodules, or bilateral sensory polyneuropathy. In all cases, correct diagnosis and adequate treatment was delayed over a period of at least 12 months. We initiated systemic antibiotics resulting in full recovery in these patients. The present case reports underscore that ACA may be associated with unusual clinical presentation which potentially result in delay of correct diagnosis and treatment. Hence, ACA diagnosis may be considerably delayed leading to inappropriate therapy exposure, prolonged patients’ suffering, and causing unnecessary cost. Thus, physicians who are not familiar with skin conditions should seek a timely dermatologist consultation.
ISSN:2673-6179
2673-6179
DOI:10.3390/dermato4020005