Recent advances in the management of ventricular tachyarrhythmias [version 1; peer review: 2 approved]

Ventricular arrhythmias are an important cause of cardiovascular morbidity and mortality, particularly in those with structural heart disease, inherited cardiomyopathies, and channelopathies. The goals of ventricular arrhythmia management include symptom relief, improving quality of life, reducing i...

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Bibliographic Details
Published in:F1000 research 2017, Vol.6, p.1027-1027
Main Authors: Batul, Syeda Atiqa, Olshansky, Brian, Fisher, John D, Gopinathannair, Rakesh
Format: Article
Language:English
Subjects:
Arrhythmias, Electrophysiology & Pacing
Cardiovascular Imaging
Cardiovascular Pharmacology
Catheters
Congenital Heart Disease
Heart Failure
Review
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Summary:Ventricular arrhythmias are an important cause of cardiovascular morbidity and mortality, particularly in those with structural heart disease, inherited cardiomyopathies, and channelopathies. The goals of ventricular arrhythmia management include symptom relief, improving quality of life, reducing implantable cardioverter defibrillator shocks, preventing deterioration of left ventricular function, reducing risk of arrhythmic death, and potentially improving overall survival. Guideline-directed medical therapy and implantable cardioverter defibrillator implantation remain the mainstay of therapy to prevent sudden cardiac death in patients with ventricular arrhythmias in the setting of structural heart disease. Recent advances in imaging modalities and commercial availability of genetic testing panels have enhanced our mechanistic understanding of the disease processes and, along with significant progress in catheter-based ablative therapies, have enabled a tailored and more effective management of drug-refractory ventricular arrhythmias. Several gaps in our knowledge remain and require further research. In this article, we review the recent advances in the diagnosis and management of ventricular arrhythmias.
ISSN:2046-1402
2046-1402
DOI:10.12688/f1000research.11202.1