Editorial of the Special Issue: Antisense Therapies

In this special issue of Biomedicines focusing on Antisense Therapies, we include insightful reviews on the state-of-the-art in relation to a number of specific diseases (in particular, Duchenne muscular dystrophy (DMD) [1,2,3], amyotrophic lateral sclerosis (ALS) [4], and fibrosis [5]), and also on...

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Bibliographic Details
Published in:Biomedicines 2018-09, Vol.6 (4), p.95
Main Author: Popplewell, Linda J
Format: Article
Language:English
Subjects:
Amyotrophic lateral sclerosis
Antisense therapy
Conflicts of interest
Cytomegalovirus
Disease
Duchenne's muscular dystrophy
Exons
Fibrosis
Gene deletion
Muscular dystrophy
Mutation
n/a
Patients
Peptides
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Summary:In this special issue of Biomedicines focusing on Antisense Therapies, we include insightful reviews on the state-of-the-art in relation to a number of specific diseases (in particular, Duchenne muscular dystrophy (DMD) [1,2,3], amyotrophic lateral sclerosis (ALS) [4], and fibrosis [5]), and also on issues that need addressing and the steps being made to overcome them. Using DMD here as an example, AOs have the potential to restore the transcript reading frame for 69% of patients with deletion mutations through the skipping of single exons. Conflicts of Interest The authors declare no conflict of interest.
ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines6040095