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Aptamer based nanobiosensors: Promising healthcare devices

Nanobiosensors based on aptamer are extensively being studied as potent analytical tools in clinical analysis. These biosensors provide high sensitivity, fast response, specificity and desired portability in addition to simplicity and decreased cost compared to conventional methods. The purpose of t...

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Bibliographic Details
Published in:Saudi pharmaceutical journal 2019-03, Vol.27 (3), p.312-319
Main Authors: Hanif, Aamir, Farooq, Rabia, Rehman, Muneeb U., Khan, Rehan, Majid, Sabhiya, Ganaie, Majid Ahmad
Format: Article
Language:English
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Summary:Nanobiosensors based on aptamer are extensively being studied as potent analytical tools in clinical analysis. These biosensors provide high sensitivity, fast response, specificity and desired portability in addition to simplicity and decreased cost compared to conventional methods. The purpose of this manuscript is to provide readers with an overview of current advances about electrochemical, electrochemiluminescent and photoelectrochemical aptasensors from the sea of available literature. These are mainly used for determination of protein-based biomarkers, especially for cancer diagnosis. Here in we have given special emphasis on nanosize-based aptasensors which have been reported to show considerable improvement in the analytical performance.
ISSN:1319-0164
2213-7475
DOI:10.1016/j.jsps.2018.11.013