Elevated PAPP-A levels in lean patients with polycystic ovary syndrome

This study aimed to evaluate the serum concentrations of PAPP-A (pregnancy associated placental protein-A), a biomarker which is associated with cardiovascular disease, in patients with polycystic ovary syndrome (PCOS). A total of 62 women with PCOS, and 68 age and body mass index (BMI) matched cont...

Full description

Saved in:
Bibliographic Details
Published in:Taiwanese journal of obstetrics & gynecology 2018-06, Vol.57 (3), p.394-398
Main Authors: Öztürk, Merve, Öktem, Mesut, Altinkaya, S. Özlem, Öktem, Emel Özalp, Elbeg, Şehri, Erdem, Ahmet, Erdem, Mehmet
Format: Article
Language:English
Subjects:
Cardiovascular risk
Polycystic ovary syndrome
Pregnancy associated pregnancy protein-A
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study aimed to evaluate the serum concentrations of PAPP-A (pregnancy associated placental protein-A), a biomarker which is associated with cardiovascular disease, in patients with polycystic ovary syndrome (PCOS). A total of 62 women with PCOS, and 68 age and body mass index (BMI) matched controls were eligible for the study. Hirsutism scores, hormonal and metabolic profile as well as PAPP-A levels were assessed in each subject. Women with PCOS and controls yielded similar median serum levels of PAPP-A (1.7 ng/ml versus 1.8 ng/ml, respectively, p = 0.328). However, when patients were compared based on BMI; subgroup analyses found that among women with BMI
ISSN:1028-4559
DOI:10.1016/j.tjog.2018.04.012