Ultrasound‐guided core needle biopsy combined with immunohistochemistry and molecular testing improve the diagnostic accuracy of bone metastases from follicular thyroid carcinoma, two case reports and analyses

Key Clinical Message Ultrasound‐guided core needle biopsy combined with immunohistochemistry and molecular testing could improve the diagnostic accuracy of bone metastases from follicular thyroid carcinoma, help to predict distant metastasis and prognosis. Metastatic thyroid follicular carcinoma pre...

Full description

Saved in:
Bibliographic Details
Published in:Clinical case reports 2024-06, Vol.12 (6), p.e8959-n/a
Main Authors: Li, Zhiyuan, Su, Jianbin, Wang, Jinjing, Yan, Li, Zhang, Huiqiang, Li, Xinyu, Tai, Yanhong, Fang, Yi, Yan, Tao
Format: Article
Language:English
Subjects:
Back pain
Biopsy
Bones
BRAF‐like malignancies
Cancer therapies
Cardiovascular Disorders
Case reports
Case Series
core needle biopsy
Endocrinology and Metabolic Disorders
follicular thyroid carcinoma
Gastroenterology/Hepatology
Histopathology
Hormone replacement therapy
immunohistochemistry
Iodine
Lymphatic system
Magnetic resonance imaging
Metastasis
RAS‐like malignancies
Scintigraphy
spinal metastases
Thyroid cancer
Thyroidectomy
Tomography
Ultrasonic imaging
Vertebrae
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Key Clinical Message Ultrasound‐guided core needle biopsy combined with immunohistochemistry and molecular testing could improve the diagnostic accuracy of bone metastases from follicular thyroid carcinoma, help to predict distant metastasis and prognosis. Metastatic thyroid follicular carcinoma presenting initially with bone lesion is uncommon, its prime symptom is gradual onset, localized pain. Patient with bone metastasis who were diagnosed before thyroidectomy had a higher rate of mortality, clinician should be cautious in eliciting the clinical history and this insidious symptom in middle age group, carry out further examination. We are presenting two case reports of a follicular thyroid carcinoma with bone metastasis, ultrasound‐guided core needle biopsy combined with immunohistochemistry (IHC) were carried out by our clinical team to determine the source and nature of the tumor, relevant literature was reviewed, molecular testing was discussed, we believe core needle biopsy combined with IHC and molecular testing improve the diagnostic accuracy of bone metastases from follicular thyroid carcinoma.
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.8959