Leishmania panamensis: a 44bp deletion in gp63 gene is found in cDNA and genomic libraries

The gp63 familiy is constituted by a group of proteins with different molecular weights depending upon the species. The importance of the major surface glycoprotein of Leishmania promastigotes, gp63, in the binding of promastigotes to macrophages has been inferred largely due to its abundance, surfa...

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Bibliographic Details
Published in:Memórias do Instituto Oswaldo Cruz 1999-09, Vol.94 (5), p.641-643
Main Authors: Hoya, R D, Trujillo, C E, Cardenas, C, Puentes, F, Patarroyo, M E, Murillo, L A
Format: Article
Language:English
Subjects:
Animals
Base Sequence
deletion
DNA sequence
Gene Deletion
Genomic Library
glycoprotein gp63
GP63
Leishmania - genetics
Leishmania guyanensis - genetics
Leishmania panamensis
major surface glycoprotein
Metalloendopeptidases - genetics
Molecular Sequence Data
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Summary:The gp63 familiy is constituted by a group of proteins with different molecular weights depending upon the species. The importance of the major surface glycoprotein of Leishmania promastigotes, gp63, in the binding of promastigotes to macrophages has been inferred largely due to its abundance, surface localization, and proteolytic activity. The nucleotide sequence data reported in this paper will appear in the GenBank Nucleotide Sequence Database under accession Nos. U62634, AF038028, AF037165, AF037166 and AF037167.
ISSN:0074-0276
0074-0276
1678-8060
DOI:10.1590/S0074-02761999000500014