Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise

• Published in: Journal of exercise science and fitness 2024-10, Vol.22 (4), p.375-382
• Main Authors: Yun, Somi, Seo, Yongsuk, Lee, Yunbin, Lee, Dae Taek
• Format: Article
• Language: English
• Subjects: Exercise intensity; Intestinal environment; Metabolic disease; Microbiome
• ISSN: 1728-869X
• DOI: 10.1016/j.jesf.2024.07.003

The purpose of this study is to investigate changes in gut microbiota related to metabolic diseases after moderate and high-intensity exercise. A total of 24 participants were divided into three groups: Non-Exercise Group (NEG, n = 8, 28.6 ± 5.3 years, 176.0 ± 7.8 cm, 81.3 ± 14.6 kg), Moderate Intensity Exercise Group (MIEG, n = 8, 26.5 ± 3.3 years, 176.9 ± 5.0 cm, 75.4 ± 9.5 kg), and Vigorous Intensity Exercise Group (VIEG, n = 8, 30.6 ± 5.9 years, 174.2 ± 3.5 cm, 77.8 ± 12.2 kg). The participants were selected by assessing physical activity, gut health status, presence of diseases, recent disease diagnoses, and dietary disorders. Those who reported any presence disease or recent disease diagnosis were excluded from the current study. Stool samples were collected after a 10-h fast for gut microbiome analysis. MIEG participants trained at 40–59 % heart rate reserve (HRR) for at least 150 min per week, while VIEG participants trained at ≥ 60 % HRR for at least 90 min per week. After 4 weeks, all participants provided stool samples for gut microbiome analysis. Data analysis was conducted using the Wilcoxon test, with statistical significance set at ≤ 0.05. The results indicated an increase in Prevotella in MIEG, while Veillonella, Dorea_formicigenerans, and Dorea_longicatena exhibited a decrease (p