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Eliciting women's preference for prenatal testing in China: a discrete choice experiment

Pregnancy tests can be used for the early diagnosis of fetal problems and can prevent abnormal birth in pregnancies. Yet, testing preferences among Chinese women are poorly investigated. We developed a Discrete Choice Experiment with 5 attributes: test procedure, detection rate, miscarriage rate, ti...

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Published in:BMC pregnancy and childbirth 2020-10, Vol.20 (1), p.604-604, Article 604
Main Authors: Wu, Liangzhi, Wu, Yanxin, Zou, Shiqian, Sun, Cong, Chen, Junyu, Li, Xueyan, Lin, Zihang, Guan, Lizhi, Zeng, Qing, Zhao, Sihan, Liang, Jingtong, Chen, Rui, Hu, Zhiwen, Au, Kingyan, Xie, Daipeng, Xiao, Xiaomin, Ming, Wai-Kit
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creator Wu, Liangzhi
Wu, Yanxin
Zou, Shiqian
Sun, Cong
Chen, Junyu
Li, Xueyan
Lin, Zihang
Guan, Lizhi
Zeng, Qing
Zhao, Sihan
Liang, Jingtong
Chen, Rui
Hu, Zhiwen
Au, Kingyan
Xie, Daipeng
Xiao, Xiaomin
Ming, Wai-Kit
description Pregnancy tests can be used for the early diagnosis of fetal problems and can prevent abnormal birth in pregnancies. Yet, testing preferences among Chinese women are poorly investigated. We developed a Discrete Choice Experiment with 5 attributes: test procedure, detection rate, miscarriage rate, time to wait for result, and test cost. By studying the choices that the women make in the hypothetical scenarios and comparing the attributes and levels, we can analyze the women's preference of prenatal testing in China. Ninety-two women completed the study. Respondents considered the test procedure as the most important attribute, followed by detection rate, miscarriage rate, wait time for result, and test cost, respectively. The estimated preference weight for the non-invasive procedure was 0.928 (P 
doi_str_mv 10.1186/s12884-020-03270-7
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Yet, testing preferences among Chinese women are poorly investigated. We developed a Discrete Choice Experiment with 5 attributes: test procedure, detection rate, miscarriage rate, time to wait for result, and test cost. By studying the choices that the women make in the hypothetical scenarios and comparing the attributes and levels, we can analyze the women's preference of prenatal testing in China. Ninety-two women completed the study. Respondents considered the test procedure as the most important attribute, followed by detection rate, miscarriage rate, wait time for result, and test cost, respectively. The estimated preference weight for the non-invasive procedure was 0.928 (P &lt; 0.0001). All other attributes being equal, the odds of choosing a non-invasive testing procedure over an invasive one was 2.53 (95% confidence interval, 2.42-2.64; P &lt; 0.001). Participants were willing to pay up to RMB$28,810 (approximately US$4610) for a non-invasive test, RMB$6061(US$970) to reduce the miscarriage rate by 1% and up to RMB$3356 (US$537) to increase the detection rate by 1%. Compared to other DCE (Discrete Choice Experiment) studies regarding Down's syndrome screening, women in our study place relatively less emphasis on test safety. The present study has shown that Chinese women place more emphasis on detection rate than test safety. Chinese women place great preference on noninvasive prenatal testing, which indicate a popular need of incorporating noninvasive prenatal testing into the health insurance coverage in China. This study provided valuable evidence for the decision makers in the Chinese government.</description><identifier>ISSN: 1471-2393</identifier><identifier>EISSN: 1471-2393</identifier><identifier>DOI: 10.1186/s12884-020-03270-7</identifier><identifier>PMID: 33032548</identifier><language>eng</language><publisher>England: BioMed Central</publisher><subject>Abortion, Spontaneous - etiology ; Abortion, Spontaneous - prevention &amp; control ; Adult ; Amniotic fluid ; China ; Choice Behavior ; Diagnostic tests ; Discrete choice experiment ; Down syndrome ; Down Syndrome - diagnosis ; Experiments ; Female ; Hospitals ; Humans ; Medical diagnosis ; Medical screening ; Miscarriage ; Obstetrics ; Patient Preference - economics ; Patient Preference - psychology ; Patient Preference - statistics &amp; numerical data ; Preferences ; Pregnancy ; Pregnancy complications ; Prenatal diagnosis ; Prenatal Diagnosis - adverse effects ; Prenatal Diagnosis - economics ; Prenatal Diagnosis - psychology ; Prenatal Diagnosis - statistics &amp; numerical data ; Questionnaires ; Software ; Statistical analysis ; Surveys and Questionnaires - statistics &amp; numerical data ; Women ; Womens health</subject><ispartof>BMC pregnancy and childbirth, 2020-10, Vol.20 (1), p.604-604, Article 604</ispartof><rights>2020. 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subjects Abortion, Spontaneous - etiology
Abortion, Spontaneous - prevention & control
Adult
Amniotic fluid
China
Choice Behavior
Diagnostic tests
Discrete choice experiment
Down syndrome
Down Syndrome - diagnosis
Experiments
Female
Hospitals
Humans
Medical diagnosis
Medical screening
Miscarriage
Obstetrics
Patient Preference - economics
Patient Preference - psychology
Patient Preference - statistics & numerical data
Preferences
Pregnancy
Pregnancy complications
Prenatal diagnosis
Prenatal Diagnosis - adverse effects
Prenatal Diagnosis - economics
Prenatal Diagnosis - psychology
Prenatal Diagnosis - statistics & numerical data
Questionnaires
Software
Statistical analysis
Surveys and Questionnaires - statistics & numerical data
Women
Womens health
title Eliciting women's preference for prenatal testing in China: a discrete choice experiment
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