Dose-Effect Relationship of Motor Nerve Inexcitability on Outcome in Guillain-Barré Syndrome: A Prospective Cohort Study

One or more inexcitable motor (IM) nerves are common during electrodiagnostic (EDx) study in Guillain-Barré syndrome (GBS). This study assessed the dose-effect relationship of IM nerves on outcome in patients with acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor and/or sensory...

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Bibliographic Details
Published in:Annals of the Indian Academy of Neurology 2023-11, Vol.26 (6), p.936-942
Main Authors: Kumar, Mritunjai, Tiwari, Ashutosh, Kumar, Shakti, Singh, Rajni
Format: Article
Language:English
Subjects:
aidp
aman
axonal
Care and treatment
Demyelination
Diagnosis
Dose-response relationship (Biochemistry)
Drug dosages
Evaluation
Guillain-Barre syndrome
guillain–barré syndrome
Immunoglobulins
inexcitable motor nerves
Inflammation
Intravenous administration
mechanical ventilation
Nerves
Neuropathy
Original
outcome
Polyneuropathy
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Summary:One or more inexcitable motor (IM) nerves are common during electrodiagnostic (EDx) study in Guillain-Barré syndrome (GBS). This study assessed the dose-effect relationship of IM nerves on outcome in patients with acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor and/or sensory axonal neuropathy (AMAN and AMSAN). Eighty-eight GBS patients admitted during May 2018-June 2023 underwent detailed clinical evaluation and EDx study. Admission and follow-up disability were assessed on a 0-10 Clinical Grading Scale (CGS). Outcome was recovery at 6 months, defined as good (CGS
ISSN:0972-2327
1998-3549
DOI:10.4103/aian.aian_641_23