Ultra-Sensitive and Specific Detection of S. aureus Bacterial Cultures Using an Oligonucleotide Probe Integrated in a Lateral Flow-Based Device

The identification of pathogens causing infectious diseases is still based on laborious and time-consuming techniques. Therefore, there is an urgent need for the development of novel methods and devices that can considerably reduce detection times, allowing the health professionals to administer the...

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Bibliographic Details
Published in:Diagnostics (Basel) 2021-10, Vol.11 (11), p.2022
Main Authors: Machado, Isabel, Goikoetxea, Garazi, Alday, Enara, Jiménez, Tania, Arias-Moreno, Xabier, Hernandez, Frank J., Hernandez, Luiza I.
Format: Article
Language:English
Subjects:
Acids
Bacteria
Bacterial infections
detection
Enzymes
Laboratories
lateral flow strips
Nosocomial infections
nuclease activity
nucleic acid probe
Pathogens
S. aureus
Staphylococcus infections
Streptococcus infections
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Summary:The identification of pathogens causing infectious diseases is still based on laborious and time-consuming techniques. Therefore, there is an urgent need for the development of novel methods and devices that can considerably reduce detection times, allowing the health professionals to administer the right treatment at the right time. Lateral flow-based systems provide fast, cheap and easy to use alternatives for diagnosis. Herein, we report on a lateral flow approach for specifically detecting S. aureus bacteria within 6 h.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics11112022