Mechanisms of Sensitive Skin and the Soothing Effects of Active Compounds: A Review

The incidence of skin sensitivity issues in human populations has increased steadily because of external factors, such as environmental changes and emotional stress. Skin sensitivity refers to a state of skin hyperreactivity that occurs under certain physiological or pathological conditions. Sensiti...

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Bibliographic Details
Published in:Cosmetics (Basel) 2024-11, Vol.11 (6), p.190
Main Authors: Chen, Bei, Tang, Haiyan, Liu, Zhihui, Qiao, Kun, Chen, Xiaoting, Liu, Shuji, Pan, Nan, Chen, Tingru, Liu, Zhiyu
Format: Article
Language:English
Subjects:
active substances
Capsaicin receptors
Cytokines
Dermatitis
Eczema
Environmental changes
Hyperreactivity
Inflammation
Mediation
Pain
Physiological aspects
Physiology
sensitive skin
Skin
Skin diseases
skin soothing
skin-barrier repair
Stress (Psychology)
TRPV1
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Summary:The incidence of skin sensitivity issues in human populations has increased steadily because of external factors, such as environmental changes and emotional stress. Skin sensitivity refers to a state of skin hyperreactivity that occurs under certain physiological or pathological conditions. Sensitive skin may manifest as redness, itching, and pain and even trigger skin diseases, such as eczema or dermatitis, in severe cases. This review discusses the sensitization mechanisms and characteristics of sensitive skin, with a focus on symptom alleviation through three key strategies: skin-barrier repair, reduction in TRPV1 receptor activity, and anti-inflammatory interventions utilizing active substances. The findings will enhance public knowledge regarding sensitive skin, promote further research and practical prevention and treatment methods, and provide theoretical support for developing soothing cosmetic products for sensitive skin.
ISSN:2079-9284
2079-9284
DOI:10.3390/cosmetics11060190