Simulated Microgravity Created Using a Random Positioning Machine Induces Changes in the Physiology of the Fusarium solani Species Complex

Fusarium is a phytopathogenic fungus involved in human pathology and is present in space stations. It is essential to understand the effects of microgravity on the physiology of this fungus to determine the potential risks to the health of crew members and to propose the necessary countermeasures. T...

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Bibliographic Details
Published in:Microorganisms (Basel) 2022-11, Vol.10 (11), p.2270
Main Authors: D’Agostino, Maurine, Babin, Anne-Lyse, Zaffino, Marie, Frippiat, Jean-Pol, Machouart, Marie, Debourgogne, Anne
Format: Article
Language:English
Subjects:
Astronauts
biofilm
Biofilms
Cell culture
Communication
Experiments
Fungi
Fusarium
Fusarium solani
Fusarium solani species complex (FSSC)
Germination
Gravitational effects
Gravitational physiology
ground-based facilities
growth
Human pathology
Immune system
Life Sciences
Medical research
Microbiology and Parasitology
Microgravity
Microscopy
Mycology
Pathogens
Physiology
Phytopathogenic fungi
Positioning devices (machinery)
random positioning machine
simulated microgravity
Space stations
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Summary:Fusarium is a phytopathogenic fungus involved in human pathology and is present in space stations. It is essential to understand the effects of microgravity on the physiology of this fungus to determine the potential risks to the health of crew members and to propose the necessary countermeasures. This study aimed to determine changes in the physiological parameters of the Fusarium solani species complex under simulated microgravity generated using a random positioning machine (RPM) and phenotypic approaches. We observed increased growth, spore production, and germination while biofilm production was reduced under RPM exposure. These in vitro data show the importance of further studying this fungus as it has been repeatedly demonstrated that microgravity weakens the immune system of astronauts.
ISSN:2076-2607
2076-2607
DOI:10.3390/microorganisms10112270