Advances in the Application of Nano-Enzymes in the Electrochemical Detection of Reactive Oxygen Species: A Review

Reactive oxygen species (ROS) play an important role in maintaining human health and are recognized as indicators of oxidative stress linked to various conditions such as neurodegenerative and cardiovascular diseases, as well as cancer. Consequently, detecting ROS levels in biological systems is cru...

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Bibliographic Details
Published in:Chemosensors 2023-08, Vol.11 (8), p.440
Main Authors: Gao, Rongwei, Bao, Shujuan
Format: Article
Language:English
Subjects:
biological objects
Biological properties
Biosensors
Carbon
Cardiovascular diseases
Chemical properties
Chemical sensors
detection
Electrochemical analysis
electrochemistry sensor
Enzymes
Graphene
Hydrogen peroxide
Identification and classification
Nanomaterials
Nanoparticles
nanozymes
Oxidation
Oxidative stress
Oxygen
Reactive oxygen species
reactive oxygen species (ROS)
Sensors
Signal transduction
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Summary:Reactive oxygen species (ROS) play an important role in maintaining human health and are recognized as indicators of oxidative stress linked to various conditions such as neurodegenerative and cardiovascular diseases, as well as cancer. Consequently, detecting ROS levels in biological systems is crucial for biomedical and analytical research. Electrochemical approaches offer promising opportunities for ROS determination due to their exceptional sensitivity, speed, and simplicity of equipment. This review covers studies using advanced electrochemical nanozyme sensors for detecting ROS in biological samples that were published over the last ten years, from 2013 to 2023. Emphasis is placed on the sensor materials and different types of modifiers employed for selective ROS detection. Furthermore, a comprehensive analysis of the sensors’ selectivity was performed.
ISSN:2227-9040
2227-9040
DOI:10.3390/chemosensors11080440