HEPATOPULMONARY SYNDROME IN PEDIATRIC PATIENTS WITH PORTAL HYPERTENSION - AN INTEGRATIVE REVIEW

• Published in: Arquivos de gastroenterologia 2024, Vol.61, p.e24040
• Main Authors: Alberto, Letícia Drumond, Fagundes, Eleonora Druve Tavares, Rodrigues, Adriana Teixeira, Queiroz, Thaís Costa Nascentes, Castro, Gustavo Valverde de, Ferreira, Alexandre Rodrigues
• Format: Article
• Language: English
• Subjects: Child; GASTROENTEROLOGY & HEPATOLOGY; Hepatopulmonary syndrome; Hepatopulmonary Syndrome - complications; Hepatopulmonary Syndrome - etiology; Humans; Hypertension, Portal - complications; Hypertension, Portal - etiology; hypoxemia; liver cirrhosis; Liver Cirrhosis - complications; Liver Transplantation; pediatrics; portal hypertension
• ISSN: 0004-2803; 1678-4219; 1678-4219
• DOI: 10.1590/S0004-2803.24612024-040

Hepatopulmonary syndrome (HPS) is characterized by the triad of abnormal arterial oxygenation caused by intrapulmonary vascular dilatations (IPVD) in the setting of advanced liver disease or portal hypertension, impacting the patient's quality of life and survival. There are still many gaps in the literature on this topic, especially in pediatrics, with practices frequently based on extrapolation of data obtained from adults. Provide a synthesis of the current knowledge about HPS in children. The research was carried out through narrative review. The databases used for the search include Medline, Embase, Elsevier, Lilacs and Scielo. The keywords used were "hepatopulmonary syndrome" AND child, children, infant, preschool, pediatric. In cirrhotic children, the prevalence of HPS can reach up to 42.5%, and it is even more common in those whose underlying condition is biliary atresia, reaching up to 63%. Screening with pulse oximetry (O2 saturation