Amniotic Fluid Volume: An Important Deciding Factor for Pregnancy Continuation in Preterm Premature Rupture of Membranes

• Published in: Journal of Applied Sciences and Clinical Practice 2024-05, Vol.5 (2), p.91-95
• Main Authors: Ken, Shweta, Gupta, Ratan, Rani, Kumari Usha, Saxena, Purnima, Yadav, Sunita, Bajaj, Bindu
• Format: Article
• Language: English
• Subjects: amniotic fluid volume; oligohydramnios; preterm; preterm premature rupture of membranes
• ISSN: 2772-364X; 2772-3658
• DOI: 10.4103/jascp.jascp_4_24

Aims and Objectives: To find out various risk factors affecting fetomaternal outcomes in preterm premature rupture of membranes (PPROM). Materials and Methods: A prospective study after approval from the ethical committee was conducted at VMMC and Safdarjung Hospital, New Delhi, Department of Obstetrics and Gynaecology from December 2020 to May 2022 in which 100 pregnant women with preterm premature rupture of membrane between 32 and 36 weeks of gestation were enrolled. Patients were followed with Total leucocyte count (TLC), urine R/M, urine C/S, high vaginal swab C/S, and C-reactive protein along with routine antenatal care investigations. Intravenous antibiotics were given to all patients for 48 h followed by oral antibiotics for 5 days. All patients were on follow-up and managed conservatively and induction of labor was done at 37 weeks or earlier in case of fetal distress and presence of signs and symptoms of chorioamnionitis. Both mother and baby were followed till 7 days after delivery. Results: In the present study, we observed the following risk factors that had adverse effects on fetomaternal outcomes in PPROM patients. The association of oligohydramnios (amniotic fluid index [AFI]