Comparative study on prevalence of metabolic syndrome based on three criteria among adults in Zhejiang province, China: an observational study

• Published in: BMJ open 2020-04, Vol.10 (4), p.e035216-e035216
• Main Authors: Wang, Xiyi, Howell, Doris, Tang, Leiwen, Shao, Jing, Ye, Zhihong
• Format: Article
• Language: English
• Subjects: Abdomen; Adolescent; Adult; Age; Aged; Aged, 80 and over; Blood pressure; Body mass index; cardiac epidemiology; China - epidemiology; Cholesterol; Comparative studies; Diabetes; Epidemiology; Estimates; Female; Females; Humans; Hypertension; Laboratories; lipid disorders; Male; Males; Medical diagnosis; Metabolic syndrome; Metabolic Syndrome - diagnosis; Metabolic Syndrome - epidemiology; Middle Aged; Obesity; Observational studies; Prevalence; Public health; Retrospective Studies; Risk Factors; Triglycerides; Young Adult
• ISSN: 2044-6055; 2044-6055
• DOI: 10.1136/bmjopen-2019-035216

ObjectivesIn this study, we aimed to estimate the prevalence of metabolic syndrome (MetS) among Chinese adults, describe the disease components and compare utility of the existing international criteria and Chinese diagnostic criteria.Design, setting and participantsA retrospective database analysis was conducted for one hospital in Zhejiang province, China. We analysed data (collected in 2017) from a total of 64 902 participants (37 500 males and 27 402 females), aged between 18 and 97 years, and who met the eligibility criteria.Main outcome measuresWe employed three criteria for MetS proposed by the International Diabetes Federation (IDF) in 2005, the 2009 Joint Scientific Statement (harmonising criteria) and the China Diabetes Society (CDS) in 2013 to detect prevalence of MetS. Specifically, we analysed waist circumference, blood pressure, fasting plasma glucose, plasma triglycerides and plasma high-density lipoprotein cholesterol.ResultsWe found an estimated age-adjusted MetS prevalence of 20.4% using IDF 2005, 30.0% based on harmonising criteria 2009 and 16.3% under the CDS 2013. This prevalence was higher in males, older adults and increased body mass index. Analysis of agreements among the criteria were 87.2% (IDF and CDS), 87.1% (IDF and harmonising criteria) and 81.6% (CDS and harmonising criteria), while their kappa coefficients were 0.641, 0.708 and 0.572 for IDF versus CDS, IDF versus harmonising criteria and CDS versus harmonising criteria, respectively. The most prevalent MetS component was abdominal obesity (50.1%), followed by dyslipidaemia (49.5%) and hypertension (46.8%) using harmonising criteria.ConclusionThese findings revealed moderate agreement among the three criteria with utility in Chinese clinical settings. The harmonising criteria 2009 performed better in early identification of MetS in the Chinese population.