Addressing Sexually Transmitted Infections Due to Neisseria gonorrhoeae in the Present and Future

It was in the 1800s when the first public publications about the infection and treatment of gonorrhoea were released. However, the first prevention programmes were only published a hundred years later. In the 1940s, the concept of vaccination was introduced into clinical prevention programmes to add...

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Bibliographic Details
Published in:Microorganisms (Basel) 2024-05, Vol.12 (5), p.884
Main Authors: Colon Perez, Julia, Villarino Fernandez, Rosa-Antia, Domínguez Lago, Adrian, Trevino Castellano, Maria Mercedes, Perez del Molino Bernal, Maria Luisa, Sanchez Poza, Sandra, Torres-Sangiao, Eva
Format: Article
Language:English
Subjects:
Antibiotics
Antimicrobial agents
Asymptomatic
Care and treatment
cephalosporin resistance
Disease prevention
Drug resistance
Gonorrhea
Infections
Infectious diseases
Inflammatory diseases
Mutation
Neisseria gonorrhoeae
Pathogens
Pelvic inflammatory disease
Penicillin
Physiological aspects
Prevention
Public health
Sexually transmitted diseases
STD
Sulfonamides
vaccine
Vaccines
Virulence
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Summary:It was in the 1800s when the first public publications about the infection and treatment of gonorrhoea were released. However, the first prevention programmes were only published a hundred years later. In the 1940s, the concept of vaccination was introduced into clinical prevention programmes to address early sulphonamide resistance. Since then, tons of publications on are undisputed, around 30,000 publications today. Currently, the situation seems to be just as it was in the last century, nothing has changed or improved. So, what are we doing wrong? And more importantly, what might we do? The review presented here aims to review the current situation regarding the resistance mechanisms, prevention programmes, treatments, and vaccines, with the challenge of better understanding this special pathogen. The authors have reviewed the last five years of advancements, knowledge, and perspectives for addressing the issue, focusing on new therapeutic alternatives.
ISSN:2076-2607
2076-2607
DOI:10.3390/microorganisms12050884