Anti-cancer effects of Gynura procumbens leaves against recurrent multiple cutaneous mast cell tumor grade III in a 7-year-old chihuahua dog

, a well-known traditional herb, has been studied to be an effective chemotherapeutic agent against a wide range of cancer cell types. A 7-year-old chihuahua dog was presented to the veterinary teaching hospital with multiple cutaneous MCT grade III masses found on the cranial aspect of the right fr...

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Bibliographic Details
Published in:Open veterinary journal (Tripoli, Libya) Libya), 2024-06, Vol.14 (6), p.1491-1496
Main Authors: Kunakornsawat, Sunee, Jermnak, Usuma
Format: Article
Language:English
Subjects:
Animals
Asteraceae
Case Report
dog
Dog Diseases - drug therapy
Dog Diseases - pathology
Dogs
Female
gynura procumbens
Male
mast cell tumor
Neoplasm Recurrence, Local - drug therapy
Neoplasm Recurrence, Local - pathology
Neoplasm Recurrence, Local - veterinary
Plant Extracts - administration & dosage
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Plant Leaves
Skin Neoplasms - drug therapy
Skin Neoplasms - pathology
Skin Neoplasms - veterinary
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Summary:, a well-known traditional herb, has been studied to be an effective chemotherapeutic agent against a wide range of cancer cell types. A 7-year-old chihuahua dog was presented to the veterinary teaching hospital with multiple cutaneous MCT grade III masses found on the cranial aspect of the right front leg and the dorsal aspect of the neck/back. Local excision of all cutaneous tumors was performed followed by chemotherapy (vinblastine, prednisone, and cyclophosphamide) every 21-day interval for 9 treatments. Nearby 3 months later, recurrent MCT was observed and lomustine was used instead for 21-day intervals. During the first chemotherapy, the dog had a fever, weak, lethargy, and vomiting. Alternative natural therapy is preferred, the dog has been receiving daily. The dog responded well to this herbal treatment. These recurrent masses began to shrink after a few weeks of treatment. After several months of treatment, all masses were completely gone. Moreover, no micro-metastasis to the lungs, spleen, and liver were detected. This natural herbal was helpful to stop the growth of tumors, to prevent micro-metastasis, and to relieve the patient's symptoms.
ISSN:2218-6050
2226-4485
2218-6050
DOI:10.5455/OVJ.2024.v14.i6.18