CellMap visualizes protein-protein interactions and subcellular localization

Many tools visualize protein-protein interaction (PPI) networks. The tool introduced here, CellMap, adds one crucial novelty by visualizing PPI networks in the context of subcellular localization, i.e. the location in the cell or cellular component in which a PPI happens. Users can upload images of...

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Bibliographic Details
Published in:F1000 research 2018-02, Vol.6, p.1824
Main Authors: Dallago, Christian, Goldberg, Tatyana, Andrade-Navarro, Miguel Angel, Alanis-Lobato, Gregorio, Rost, Burkhard
Format: Article
Language:English
Subjects:
Bioinformatics
Chemical Biology of the Cell
Informatics
Localization
Protein interaction
Proteins
Software Tool
Visualization
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Description
Summary:Many tools visualize protein-protein interaction (PPI) networks. The tool introduced here, CellMap, adds one crucial novelty by visualizing PPI networks in the context of subcellular localization, i.e. the location in the cell or cellular component in which a PPI happens. Users can upload images of cells and define areas of interest against which PPIs for selected proteins are displayed (by default on a cartoon of a cell). Annotations of localization are provided by the user or through our in-house database. The visualizer and server are written in JavaScript, making CellMap easy to customize and to extend by researchers and developers.
ISSN:2046-1402
2046-1402
DOI:10.12688/f1000research.12707.2