Sapindus Mukurossi - An Effective Biocleanser for Removable Dental Prostheses? An In vitro Study

This study aims to determine the efficient concentration of Sapindus mukorossi that can be used as a denture cleanser. 60 heat cure denture base resin specimens of dimensions 10*10*2 mm were fabricated. Among these, 30 were fabricated by compression moulding technique and the remaining 30 by an inje...

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Bibliographic Details
Published in:Journal of pharmacy & bioallied science 2024-04, Vol.16 (Suppl 2), p.S1154-S1160
Main Authors: Hariharan, Annapoorni, Krishnamurthi, Sowmya, Thamarai, C, Thanya, K, Parameswari, Devi, Krithika, A
Format: Article
Language:English
Subjects:
Analysis
anti-microbial activity
Candida albicans
Cleaning compounds
Colonies
Compression
compression moulding
denture cleansers
Dentures
Herbal medicine
Implants, Artificial
injection moulding
Medicine, Botanic
Medicine, Herbal
Original Research
Plant extracts
Prosthesis
Prosthetics
Sapindus mukorossi
Statistical analysis
Streptococcus mutans
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Summary:This study aims to determine the efficient concentration of Sapindus mukorossi that can be used as a denture cleanser. 60 heat cure denture base resin specimens of dimensions 10*10*2 mm were fabricated. Among these, 30 were fabricated by compression moulding technique and the remaining 30 by an injection moulding technique. The samples inoculated with Candida albicans and Streptococcus mutans were subjected to denture cleansing protocols using a medicinal herbal extract from the Sapindus mukorossi, at various concentrations [15%, 20%, and 25%]. The colony-forming unit [CFU] values were evaluated using a microprocessor colony counter. The statistical analysis was performed. The intragroup comparison showed a statistically significant difference between all groups except the compression moulded samples inoculated with Streptococcus mutans. The intergroup comparison revealed no statistically significant differences between the compared groups. The reduction in CFU values is evident in the effective anti-microbial activity of Sapindus mukorossi. A concentration of 25% Sapindus mukorossi solution showed the greatest efficiency. The maximum anti-microbial activity was observed against Candida albicans in a 25% concentration of Sapindus mukorossi. Among all, injection moulded samples showed better results.
ISSN:0976-4879
0975-7406
DOI:10.4103/jpbs.jpbs_1189_23