Hypertriglyceridemia and hyperuricemia: a retrospective study of urban residents

• Published in: Lipids in health and disease 2019-04, Vol.18 (1), p.81-81, Article 81
• Main Authors: Hou, Yan-Long, Yang, Xiao-Lan, Wang, Chun-Xia, Zhi, Li-Xia, Yang, Mei-Juan, You, Chong-Ge
• Format: Article
• Language: English
• Subjects: Alcohol; Analysis; Arthritis; Bisphenol A; Cardiovascular disease; Cholesterol; Confidence intervals; Diabetes; Females; Health; Health risk assessment; Hyperlipidemia; Hypertension; Hypertriglyceridemia; Hyperuricemia; Hyperuricemia; triglyceride; Lipoproteins; Males; Metabolic disorders; Metabolism; Middle age; Obesity; Personnel selection; Population; Prevalence studies (Epidemiology); Purines; Regression analysis; Rheumatism; Risk factors; Systematic review; Triglycerides; Uric acid; Womens health
• ISSN: 1476-511X; 1476-511X
• DOI: 10.1186/s12944-019-1031-6

The aim of this study was to determine the association between hypertriglyceridemia and hyperuricemia (HUA). The study was conducted in 3884 subjects who had not received medication enrolled as a baseline. Each participant received at least three annual health check-ups between 2011 and 2017. The risk of hyperuricemia was assessed in four Quartiles (Q1 to Q4) according to TG levels using multivariate-adjusted logistic regression models. The total incidence rate of HUA was 62.3/1000 person-years. In the univariate analysis, the risk of hyperuricemia in people with hypertriglyceridemia was 2.353 times that of normal triglycerides, with a 95% confidence interval of (2.011, 2.754), and the risk of hyperuricemia in men was 1.86 times of female, and the 95% confidence interval is (1.634, 2.177). After adjusting the potential confounders, the relative risk RR of TG at Q2 Q3 Q4 was 1.445 (95%CI:1.114, 1.901), 2.075 (1.611, 2.674), 2.972 (2.322, 3.804). TG is an independent risk factor for hyperuricemia. As the level of TG increases, the risk of HUA increases.