Limited Joint Mobility Progression in Type 1 Diabetes: A 15-Year Follow-Up Study

Objective. To assess the evolution of joint mobility over a period of 15 years in type 1 diabetic patients and healthy controls and to determine whether microalbuminuria is associated with a different evolution of joint mobility. Methods. Joint mobility of hand and wrist was determined in 63 patient...

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Bibliographic Details
Published in:International journal of endocrinology 2018-01, Vol.2018 (2018), p.1-5
Main Authors: Nolla, Joan M., Garcia-Sancho, Paula, Rozadilla, Antoni, Labad, Javier, Montanya, Eduard
Format: Article
Language:English
Subjects:
Age
Blood pressure
Development and progression
Diabetes
Diabetic retinopathy
Diabetics
Endocrinology
Glycosylated hemoglobin
Hypertension
Metabolism
Studies
Type 1 diabetes
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Summary:Objective. To assess the evolution of joint mobility over a period of 15 years in type 1 diabetic patients and healthy controls and to determine whether microalbuminuria is associated with a different evolution of joint mobility. Methods. Joint mobility of hand and wrist was determined in 63 patients with type 1 diabetes and 63 healthy subjects. Fifteen years later, 37 (58.7%) diabetic patients and 16 (25.4%) healthy subjects were studied again. Joint mobility was assessed with the Prayer sign and by measuring the angle of maximal flexion of the fifth and third metacarpophalangeal (MCP) joints and wrist. Patients with diabetes were visited 2–4 times every year with regular assessment of glycated hemoglobin (HbA1c), urinary albumin excretion (UAE), and ophthalmoscopy. Results. Fifteen years after the initial exam, diabetic patients showed reduced flexion of the fifth MCP joint (82.6 ± 5.8 versus 76.0 ± 6.4 degrees, p
ISSN:1687-8337
1687-8345
DOI:10.1155/2018/1897058