Greener Grass: The Modern History of Epithelial Stem Cell Innovation

The field of epithelial stem cell development has been irrevocably shaped by the work of American scientist Howard Green, whose breakthroughs in stem cell culture methods translated to therapeutic practice. In this review, we chronicle the milestones that propelled the field of regenerative medicine...

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Bibliographic Details
Published in:Life (Basel, Switzerland) Switzerland), 2023-03, Vol.13 (3), p.688
Main Authors: Pitt, Keshia, Mochida, Yoshiyuki, Senoo, Makoto
Format: Article
Language:English
Subjects:
Albinism
Artificial skin
Cell culture
cultured epithelial autografts
Embryos
epithelia
Epithelial cells
Fibroblasts
Hair
Health aspects
History
holoclones
Homeostasis
Methods
Microscopy
p63
Physiological aspects
Regenerative medicine
repsox
Review
Scientists
Skin
Skin-grafting
Stem cell research
Stem cells
Thymus gland
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Summary:The field of epithelial stem cell development has been irrevocably shaped by the work of American scientist Howard Green, whose breakthroughs in stem cell culture methods translated to therapeutic practice. In this review, we chronicle the milestones that propelled the field of regenerative medicine of the skin forward over the last fifty years. We detail the early discoveries made by Green and his collaborators, highlight clinical cases that made life-saving use of his findings, and discuss the accomplishments of other scientists who later innovated upon his discoveries.
ISSN:2075-1729
2075-1729
DOI:10.3390/life13030688