Case for diagnosis. Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder

Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder is a rare disease, with an indolent evolution and benign course. The classic presentation is a solitary nodule on the face or trunk. The disorder’s rarity and clinical and histopathological characteristics, can make the diagnosi...

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Bibliographic Details
Published in:Anais brasileiros de dermatología 2019-01, Vol.94 (1), p.99-101
Main Authors: Valentim, Flávia de Oliveira, Oliveira, Cristiano Claudino, Miot, Hélio Amante
Format: Article
Language:English
Subjects:
Adult
CD4-Positive T-Lymphocytes - pathology
DERMATOLOGY
Erythema - pathology
Female
Humans
Immunohistochemistry
Lymphoma
Lymphoma, T-Cell, Cutaneous - pathology
Lymphoproliferative disorders
Lymphoproliferative Disorders - pathology
Pseudolymphoma
Skin Neoplasms - pathology
What Is Your Diagnosis?
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Summary:Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder is a rare disease, with an indolent evolution and benign course. The classic presentation is a solitary nodule on the face or trunk. The disorder’s rarity and clinical and histopathological characteristics, can make the diagnosis difficult. We present the case of a 36-year-old Caucasian woman with a purplish erythematous nodule, hardened, shiny, asymptomatic, on the left nasal ala, which had grown progressively for 45 days. Histopathological examination and immunohistochemistry panel demonstrated alterations consistent with primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder. There was complete remission of the condition within 60 days of treatment with potent occlusive corticosteroids.
ISSN:0365-0596
1806-4841
1806-4841
DOI:10.1590/abd1806-4841.20198513