Evaluation of cytotoxicity and antibacterial activity of different pulp capping liners

This study compares the cytotoxicity and antibacterial activity of five pulp capping liners. This study was conducted on Fuji II LC glass ionomer, Dycal, Calcimol LC, TheraCal LC, and ACTIVA BioACTIVE. For cytotoxicity, the (MTT) methyl thiazolyl tetrazolium assay was performed on 3 samples from eac...

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Bibliographic Details
Published in:Biomaterial investigations in dentistry 2023, Vol.10 (1), p.2287019-2287019
Main Authors: Moradi, Zohre, Abbasi, Mahdi, Bahador, Abbas, Yekaninejad, Mir Saeed, Khanghah, Xaniar Mohammadi, Hoseini, Amirahmad Pahlavan, Ranjbar Omrani, Ladan
Format: Article
Language:English
Subjects:
ACTIVA BioACTIVE-BASE LINER
anti-bacterial agents
Dental pulp capping
Lactobacillus casei
MTT formazan
Original
Streptococcus mutans
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Summary:This study compares the cytotoxicity and antibacterial activity of five pulp capping liners. This study was conducted on Fuji II LC glass ionomer, Dycal, Calcimol LC, TheraCal LC, and ACTIVA BioACTIVE. For cytotoxicity, the (MTT) methyl thiazolyl tetrazolium assay was performed on 3 samples from each group of human dental pulp cells (HDPSCs) after 24 h of incubation. The direct contact test (DCT) for antibacterial activity, 6 samples (3 for each material, and 3 for negative control), from each liner were made to evaluate ( ), ( ), and ( ). Data were analyzed by one-way ANOVA and Tukey's post-hoc test (alpha = 0.05). Data analysis showed that the cytotoxicity of the materials was significantly different (  
ISSN:2641-5275
2641-5275
DOI:10.1080/26415275.2023.2287019