The Extracellular Protein, Transthyretin Is an Oxidative Stress Biomarker

The extracellular protein, transthyretin is responsible for the transport of thyroxin and retinol binding protein complex to the various parts of the body. In addition to this transport function, transthyretin has also been involved in cardiovascular malfunctions, polyneuropathy, psychological disor...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in physiology 2019, Vol.10, p.5-5
Main Authors: Sharma, Meesha, Khan, Sheeza, Rahman, Safikur, Singh, Laishram Rajendrakumar
Format: Article
Language:English
Subjects:
biomarker
cryptic protease activity
oxidative stress
Physiology
retinol binding protein
thyroxin
transthyretin
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The extracellular protein, transthyretin is responsible for the transport of thyroxin and retinol binding protein complex to the various parts of the body. In addition to this transport function, transthyretin has also been involved in cardiovascular malfunctions, polyneuropathy, psychological disorders, obesity and diabetes, etc. Recent developments have evidenced that transthyretin has been associated with many other biological functions that are directly or indirectly associated with the oxidative stress, the common hallmark for many human diseases. In this review, we have attempted to address that transthyretin is associated with oxidative stress and could be an important biomarker. Potential future perspectives have also been discussed.
ISSN:1664-042X
1664-042X
DOI:10.3389/fphys.2019.00005