Construction and Validation of a Nomogram to Predict the Postoperative Venous Thromboembolism Risk in Patients with HGSOC

Venous thromboembolism (VTE) is a common complication in patients with high-grade serous ovarian cancer (HGSOC) after surgery. This study aims to establish a comprehensive risk assessment model to better identify the potential risk of postoperative VTE in HGSOC. Clinical data from 587 HGSOC patients...

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Bibliographic Details
Published in:Clinical and applied thrombosis/hemostasis 2024-01, Vol.30, p.10760296241255958-10760296241255958
Main Authors: Huang, Zhen, Li, Ling, Gong, Zhengxin, Tang, Liangdan
Format: Article
Language:English
Subjects:
Adult
Aged
Female
Humans
Middle Aged
Nomograms
Original
Ovarian Neoplasms - surgery
Postoperative Complications - etiology
Regression analysis
Retrospective Studies
Risk Assessment - methods
Risk Factors
Thromboembolism
Venous Thromboembolism - epidemiology
Venous Thromboembolism - etiology
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Summary:Venous thromboembolism (VTE) is a common complication in patients with high-grade serous ovarian cancer (HGSOC) after surgery. This study aims to establish a comprehensive risk assessment model to better identify the potential risk of postoperative VTE in HGSOC. Clinical data from 587 HGSOC patients who underwent surgical treatment were retrospectively collected. Univariate and multivariate logistic regression analyses were performed to identify independent factors influencing the occurrence of postoperative VTE in HGSOC. A nomogram model was constructed in the training set and further validated in the verification set. Logistic regression identified age (odds ratio [OR] = 1.063, P = .002), tumor size (OR = 3.815, P 
ISSN:1076-0296
1938-2723
DOI:10.1177/10760296241255958